Impact of the intensity of microemboli on neurocognitive outcome following cardiopulmonary bypass

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dc.contributor.authorDoganci, Suat
dc.contributor.authorGünaydın, Serdar
dc.contributor.authorKocak, Orhan Murat
dc.contributor.authorYilmaz, Seyhan
dc.contributor.authorDemirkılıç, Ufuk
dc.date.accessioned2020-06-25T18:07:20Z
dc.date.available2020-06-25T18:07:20Z
dc.date.issued2013
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: This study aimed to determine whether there was any association between the intensity of intraoperative gaseous microembolic signals (GME), neuropsychological testing and clinical outcome in high-risk patients undergoing coronary artery surgery (CABG). Methods: Over a 6-month period, GME activity was monitored in 102 Euroscore 6+ patients during cardiopulmonary bypass (CPB) with a conventional 32-micron arterial filter by non-invasive, real-time ultrasonic device. Cognitive tests; line bisection, the Stroop test, finger tapping, and the Rey Auditory Verbal Learning Test were performed at baseline, postoperative one week and postoperative one month. Results: The distribution of GME activity showed that there were three groups of patients: >500 total emboli (n = 38); 250 to 500 emboli (n = 30) and <250 emboli (n = 34) at a detection level of 2% of the circuit diameter on the arterial side. Line bisection, the Stroop test and finger tapping were impaired significantly in >500 emboli patients versus control (<250 emboli) in postoperative week one, but resolved in one month. Conclusions: Correlation between intraoperative GME intensity and neurocognitive tests suggests that the level of GME might have a role in determining the psychological outcome after CABG with CPB.en_US
dc.description.sponsorshipUniversity of Kirikkale Research FundKirikkale Universityen_US
dc.description.sponsorshipThis study is supported by University of Kirikkale Research Fund.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1177/0267659112470693
dc.identifier.endpage262en_US
dc.identifier.issn0267-6591
dc.identifier.issue3en_US
dc.identifier.pmid23381348
dc.identifier.scopus2-s2.0-84876696396
dc.identifier.scopusqualityQ1
dc.identifier.startpage256en_US
dc.identifier.urihttps://doi.org/10.1177/0267659112470693
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5545
dc.identifier.volume28en_US
dc.identifier.wosWOS:000317988500013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Ltden_US
dc.relation.ispartofPerfusion-Uk
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcoronary artery bypass graftingen_US
dc.subjectembolismen_US
dc.subjectneurocognitive deficitsen_US
dc.titleImpact of the intensity of microemboli on neurocognitive outcome following cardiopulmonary bypassen_US
dc.typeArticle

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