Impact of the intensity of microemboli on neurocognitive outcome following cardiopulmonary bypass
dc.contributor.author | Doganci, Suat | |
dc.contributor.author | Günaydın, Serdar | |
dc.contributor.author | Kocak, Orhan Murat | |
dc.contributor.author | Yilmaz, Seyhan | |
dc.contributor.author | Demirkılıç, Ufuk | |
dc.date.accessioned | 2020-06-25T18:07:20Z | |
dc.date.available | 2020-06-25T18:07:20Z | |
dc.date.issued | 2013 | |
dc.department | Kırıkkale Üniversitesi | |
dc.description.abstract | Background: This study aimed to determine whether there was any association between the intensity of intraoperative gaseous microembolic signals (GME), neuropsychological testing and clinical outcome in high-risk patients undergoing coronary artery surgery (CABG). Methods: Over a 6-month period, GME activity was monitored in 102 Euroscore 6+ patients during cardiopulmonary bypass (CPB) with a conventional 32-micron arterial filter by non-invasive, real-time ultrasonic device. Cognitive tests; line bisection, the Stroop test, finger tapping, and the Rey Auditory Verbal Learning Test were performed at baseline, postoperative one week and postoperative one month. Results: The distribution of GME activity showed that there were three groups of patients: >500 total emboli (n = 38); 250 to 500 emboli (n = 30) and <250 emboli (n = 34) at a detection level of 2% of the circuit diameter on the arterial side. Line bisection, the Stroop test and finger tapping were impaired significantly in >500 emboli patients versus control (<250 emboli) in postoperative week one, but resolved in one month. Conclusions: Correlation between intraoperative GME intensity and neurocognitive tests suggests that the level of GME might have a role in determining the psychological outcome after CABG with CPB. | en_US |
dc.description.sponsorship | University of Kirikkale Research FundKirikkale University | en_US |
dc.description.sponsorship | This study is supported by University of Kirikkale Research Fund. | en_US |
dc.identifier.citation | closedAccess | en_US |
dc.identifier.doi | 10.1177/0267659112470693 | |
dc.identifier.endpage | 262 | en_US |
dc.identifier.issn | 0267-6591 | |
dc.identifier.issue | 3 | en_US |
dc.identifier.pmid | 23381348 | |
dc.identifier.scopus | 2-s2.0-84876696396 | |
dc.identifier.scopusquality | Q1 | |
dc.identifier.startpage | 256 | en_US |
dc.identifier.uri | https://doi.org/10.1177/0267659112470693 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12587/5545 | |
dc.identifier.volume | 28 | en_US |
dc.identifier.wos | WOS:000317988500013 | |
dc.identifier.wosquality | Q4 | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.indekslendigikaynak | PubMed | |
dc.language.iso | en | |
dc.publisher | Sage Publications Ltd | en_US |
dc.relation.ispartof | Perfusion-Uk | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | coronary artery bypass grafting | en_US |
dc.subject | embolism | en_US |
dc.subject | neurocognitive deficits | en_US |
dc.title | Impact of the intensity of microemboli on neurocognitive outcome following cardiopulmonary bypass | en_US |
dc.type | Article |
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