The effect of steroid and intravenous immunoglobulin on thrombopoietin levels in pediatric patients with immune thrombocytopenic purpura

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dc.contributor.authorKocak, U
dc.contributor.authorGursel, T
dc.contributor.authorOzturk, G
dc.date.accessioned2020-06-25T17:34:43Z
dc.date.available2020-06-25T17:34:43Z
dc.date.issued2000
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThrombopoietin (TPO), which is the main regulator of megakaryo/thrombopoiesis, has been recently cloned and purified, and shown to be useful in discriminating thrombocytopenia due to decreased production or increased platelet destruction. However, there are no detailed investigations about the drug effects on TPO levels during childhood. This study was conducted to measure the TPO levels of children with immune thrombocytopenic purpura (ITP) during steroid and immunoglobulin treatment. Twelve patients with acute ITP were treated with high-dose methyl prednisolone and five patients were treated with intravenous immunoglobulin. Neither steroids nor immunoglobulin were found to have any effect on TPO levels. Blood Coag Fibrinol 11:121-125 (C) 2000 Lippincott Williams & Wilkins.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage125en_US
dc.identifier.issn0957-5235
dc.identifier.issue2en_US
dc.identifier.pmid10759004
dc.identifier.scopus2-s2.0-0034003035
dc.identifier.scopusqualityQ3
dc.identifier.startpage121en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2863
dc.identifier.volume11en_US
dc.identifier.wosWOS:000086469800002
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofBlood Coagulation & Fibrinolysis
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectsteroiden_US
dc.subjectintravenous immunoglobulinen_US
dc.subjectimmune thrombocytopenic purpuraen_US
dc.subjectthrombopoietinen_US
dc.subjectchildhooden_US
dc.titleThe effect of steroid and intravenous immunoglobulin on thrombopoietin levels in pediatric patients with immune thrombocytopenic purpuraen_US
dc.typeArticle

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