Investigation on Efficacy of a Commercial Vaccine for Treatment of Leptospirosis in Cattle

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Tarih

2010

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Medwell Online

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

The aim of this study was to determinate leptospirosis in cattle and to investigate efficacy of a commercial vaccine in treatment of leptospirosis. Upon observing leptosipirosis specific clinical signs including haematuria and mucosal icterus in 2 heifers and mouse fleshes on the surface of the water reserve of the farm, the clinicians tentatively diagnosed the diseased heifers as leptosiprosis. In addition, 9 heifers had general clinical signs including fever, apathy and tachypnea. Blood samples were collected from 41 heifers kept in the farm, including those exhibiting specific and non-specific clinical signs. All clinically diseased heifers were seropositive for leptospirosis confirmed by Microagglutination Test (MAT). The antibody titers were 1/100 or above in 11 out of 41 heifers (26.8%). All 41 heifers were vaccinated with a specific commercial vaccine (Lepto Shield 5 (R)) developed against leptospirosis. At the forth day of vaccination, one of the diseased heifers died of acute leptospirosis while the others clinically recovered 8 days after vaccination and none of the seropositive heifers showed any clinical signs of the disease. No side effects were observed within a month following vaccination. The results of the present study suggest that Lepto Shield 5 (R) is effective not only for protection but also for treatment of leptospirosis in cattle.

Açıklama

GAZYAGCI, SERKAL/0000-0002-0043-6942

Anahtar Kelimeler

Cattle, Lepto Shield 5 (R), leptospirosis, prognosis, treatment, vaccination

Kaynak

Journal Of Animal And Veterinary Advances

WoS Q Değeri

Q3

Scopus Q Değeri

N/A

Cilt

9

Sayı

10

Künye

closedAccess