Effects of boric acid on experimental periodontitis and alveolar bone loss in rats

Basit Öğe Kaydı
dc.contributor.authorDemirer, Serhat
dc.contributor.authorKara, M. Isa
dc.contributor.authorErciyas, Kamile
dc.contributor.authorOzdemir, Hakan
dc.contributor.authorOzer, Hatice
dc.contributor.authorAy, Sinan
dc.date.accessioned2020-06-25T18:06:52Z
dc.date.available2020-06-25T18:06:52Z
dc.date.issued2012
dc.departmentKırıkkale Üniversitesi
dc.descriptionerciyas, kamile/0000-0001-9940-0423
dc.description.abstractObjective: The goal of the present study was to evaluate the histopathologic and morphometric effects of systemic boric acid in a rat periodontitis model. Design: Twenty-four Wistar rats were divided into three groups of eight animals each: non-ligated (NL), ligature only (LO), and ligature and treated with boric acid (BA) (3 mg/kg per day for 11 days). A 4/0 silk suture was placed in a subgingival position around the mandibular first molars; after 11 days the rats were sacrificed, and changes in alveolar bone levels were measured clinically and tissues were histopathologically examined to assess the differences amongst the study groups. Results: The ratio of presence of inflammatory cell infiltration (ICI) and osteoclast number in the LO group was significantly higher than that of the NL and BA groups (p < 0.05). The ratio of presence of osteoblastic activity in the LO group was significantly lower than that of the NL and BA groups (p < 0.05). Alveolar bone loss was also significantly higher in the LO group compared to the BA and NL groups (p < 005). Conclusions: This study has demonstrated that systemic administration of boric acid reduced periodontal inflammation and alveolar bone loss in periodontal disease in rats. (C) 2011 Elsevier Ltd. All rights reserved.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.archoralbio.2011.07.012
dc.identifier.endpage65en_US
dc.identifier.issn0003-9969
dc.identifier.issn1879-1506
dc.identifier.issue1en_US
dc.identifier.pmid21871607
dc.identifier.scopus2-s2.0-84155167665
dc.identifier.scopusqualityQ1
dc.identifier.startpage60en_US
dc.identifier.urihttps://doi.org/10.1016/j.archoralbio.2011.07.012
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5386
dc.identifier.volume57en_US
dc.identifier.wosWOS:000300122800009
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofArchives Of Oral Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectExperimental periodontitisen_US
dc.subjectRaten_US
dc.subjectOxidative stressen_US
dc.subjectAntioxidanten_US
dc.titleEffects of boric acid on experimental periodontitis and alveolar bone loss in ratsen_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Effects of boric acid on experimental periodontitis and alveolar bone loss in rats.pdf
Boyut:
819.62 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu