Plasma adrenomedullin levels in patients with polycystic ovary syndrome

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dc.contributor.authorUçar, Banu
dc.contributor.authorNoyan, Volkan
dc.contributor.authorCağlayan, Osman
dc.contributor.authorYücel, Aykan
dc.contributor.authorSagsöz, Nevin
dc.date.accessioned2020-06-25T17:41:25Z
dc.date.available2020-06-25T17:41:25Z
dc.date.issued2006
dc.descriptionYucel, Aykan/0000-0002-5888-692X
dc.description.abstractObjective: To evaluate adrenomedullin levels in patients. with polycystic ovary syndrome (PCOS). Design: Prospective study. Setting: Department of obstetrics and gynecology in a university hospital. Patient(s): Thirty-eight women with PCOS and 29 healthy control subjects were enrolled in the study. Intervention(s): Plasma. adrenomedullin, serum androstenedione, free T, T, DHEAS, SHBG, thyrotropin, PRL, FSH, LH, and E-2 were measured in each subject. Insulin resistance was estimated by fasting insulin level, fasting glucose:insulin ratio and 75-g glucose tolerance test for 2 hours. Main Outcome Measure(s): Plasma adrenomedullin levels and, correlations among adrenomullin and gonadotropins , female sex steroids, androgens, and insulin resistance. Result(s): There was no significant difference concerning plasma adrenomullin concentrations between the groups. In patients with PCOS, fasting glucose, fasting insulin, body mass index, and free T were inversely 179 y correlated with glue correlated with the plasma adrenomedullin. Plasma adrenomedullin was significantly correlated with glucose: insulin ratio. After controlling for, body mass index, there were no significant correlations between the above-mentioned parameters. Conclusion(s): Adrenomedullin may play a role in regulating the insulin metabolism in patients with PCOS.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.fertnstert.2006.02.119
dc.identifier.endpage948en_US
dc.identifier.issn0015-0282
dc.identifier.issue4en_US
dc.identifier.pmid16963041
dc.identifier.scopus2-s2.0-33749267612
dc.identifier.scopusqualityQ1
dc.identifier.startpage942en_US
dc.identifier.urihttps://doi.org10.1016/j.fertnstert.2006.02.119
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3707
dc.identifier.volume86en_US
dc.identifier.wosWOS:000241165400022
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Science Incen_US
dc.relation.ispartofFertility And Sterility
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpolycystic ovary syndromeen_US
dc.subjectadrenomedullinen_US
dc.subjectinsulin resistanceen_US
dc.subjectobesityen_US
dc.titlePlasma adrenomedullin levels in patients with polycystic ovary syndromeen_US
dc.typeArticle

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