Investigation of atypical bacteria and virus antigens in respiratory tract infections by use of an immunofluorescence method

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dc.contributor.authorKaygusuz, S
dc.contributor.authorKoksal, I
dc.contributor.authorAydin, K
dc.contributor.authorCaylan, R
dc.date.accessioned2020-06-25T17:40:09Z
dc.date.available2020-06-25T17:40:09Z
dc.date.issued2004
dc.departmentKırıkkale Üniversitesi
dc.description.abstractIn this study an immunofluorescence (IF) method was used to investigate the antigens of viruses and atypical bacteria in respiratory tract infections (RTI) in pediatric and adult age groups. In this prospective study of 2 years (1998 - 2000), IF was used to investigate the antigens of 7 viral and 3 atypical bacteria to be used for the etiological diagnosis of RTI. Sputum (33.6%) and nasopharyngeal aspirate specimens were obtained from pediatric patients (Group I, 76 cases) and adults (Group II, 135 cases) with RTI symptoms. Antigen detection rates were found to be 44.7% in Group I and 67.4% in Group II (P < 0.05). The following rates for specific antigens in Groups I and II, respectively, were as follows: Chlamydia pneumoniae, 17.1 and 13.3% (P > 0.05); Mycoplasma pneumoniae, 0 and 9.6% (P < 0.05); influenza A virus, 3.9 and 16.3% (P < 0.05); adenovirus, 3.9 and 14.8% (P < 0.05); parainfluenza virus type 1, 5.3 and 7.4% (P > 0.05); respiratory syncytial virus, 9.2 and 1.5% (P < 0.05); parainfluenza virus type 2, 3.9 and 3% (P > 0.05); and influenza B virus, 1.3 and 1.5% (P > 0.05). Mixed agents were found at a rate of 2.6 and 3.7% (P > 0.05) in Groups I and II, respectively. Parainfluenza virus type 3 and Legionella pneumophila antigens were not found. Since detecting etiological agents provides an important guide for determining the most appropriate antibiotic therapy, this IF method could be applied in clinical practice for arriving at a correct diagnosis and administration of effective treatment.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage36en_US
dc.identifier.issn1344-6304
dc.identifier.issn1884-2836
dc.identifier.issue2en_US
dc.identifier.pmid15118204
dc.identifier.scopus2-s2.0-2542437781
dc.identifier.scopusqualityQ2
dc.identifier.startpage33en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3314
dc.identifier.volume57en_US
dc.identifier.wosWOS:000221138100001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherNatl Inst Infectious Diseasesen_US
dc.relation.ispartofJapanese Journal Of Infectious Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleInvestigation of atypical bacteria and virus antigens in respiratory tract infections by use of an immunofluorescence methoden_US
dc.typeArticle

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