Oxidative stress in patients with chronic renal failure: Effects of hemodialysis

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dc.contributor.authorDurak, I
dc.contributor.authorKacmaz, M
dc.contributor.authorElgun, S
dc.contributor.authorOzturk, HS
dc.date.accessioned2020-06-25T17:40:14Z
dc.date.available2020-06-25T17:40:14Z
dc.date.issued2004
dc.departmentKırıkkale Üniversitesi
dc.descriptionOZTURK, HASAN SERDAR/0000-0001-8356-9224; Elgun, Serenay/0000-0002-1751-090X
dc.description.abstractObjective: To investigate blood oxidative status of patients with chronic renal failure (CRF) and possible effects of hemodialysis on the development of oxidative stress in blood. Materials and Methods: The levels of malondialdehyde (MDA) and oxidation resistance (OR) values were measured in blood plasma, erythrocyte hemolysate and erythrocyte membrane fractions of 33 patients with CRF and of 12 healthy controls. Of the 33 patients, 17 subjects were under hemodialysis treatment. Results: MDA levels were found to be increased in all blood fractions of the patients. OR values were unchanged in erythrocyte hemolysates but decreased in plasma and erythrocyte membrane fractions of the CRF patients. Moreover, erythrocyte MDA levels were determined to be higher in hemodialyzed patients compared with both controls and non-hemodialyzed patients. OR values were lower in all blood fractions of the hemodialyzed patients relative to controls and non-hemodialyzed patients. Conclusion: Results suggest that there is a significant oxidative stress (expressed as peroxidation) in blood samples from patients with CRF, which is further exacerbated by hemodialysis. Copyright (C) 2004 S. Karger AG, Basel.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1159/000075634
dc.identifier.endpage87en_US
dc.identifier.issn1011-7571
dc.identifier.issue2en_US
dc.identifier.pmid14755140
dc.identifier.scopus2-s2.0-1042301221
dc.identifier.scopusqualityQ1
dc.identifier.startpage84en_US
dc.identifier.urihttps://doi.org/10.1159/000075634
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3355
dc.identifier.volume13en_US
dc.identifier.wosWOS:000188600400006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKargeren_US
dc.relation.ispartofMedical Principles And Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectchronic renal failureen_US
dc.subjecthemodialysisen_US
dc.subjectoxidative stressen_US
dc.titleOxidative stress in patients with chronic renal failure: Effects of hemodialysisen_US
dc.typeArticle

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