Tetanus IgG antibody levels in children aged 12 to 47 months in Turkey

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dc.contributor.authorYıldırım, R.C.
dc.contributor.authorYılmaz, N.
dc.contributor.authorYildirim, U
dc.contributor.authorAksakal, FN
dc.date.accessioned2020-06-25T17:34:51Z
dc.date.available2020-06-25T17:34:51Z
dc.date.issued2001
dc.departmentKırıkkale Üniversitesi
dc.description.abstractTetanus is a serious disease with high mortality, which is very difficult to treat but can be prevented easily by vaccination. The number of tetanus cases reported in Turkey was 42 in 1996 and 51 in 1997. This study was carried out on children aged 12 to 47 months who have vaccination cards in the No. 1 Health Centre in Batikent district in Ankara, Turkey. Forty-one of the children had received 3 doses (Group I) of tetanus vaccine, and 47 of them had received 4 doses of the vaccine (Group 2). Anti-toroid IgG antibody in blood sera was quantified by using the enzyme-linked immunosorbent assay technique. In Group 1. antibody levels more than 0.01 IU/mL were found in 47%, 43%, and 45% of blood sera of children aged 12 to 23 months, 24 to 35 months, and 36 to 47 months, respectively. These rates in Group 2 were found to be 91%. 88%, and 60%, respectively. The protective antibody response (>1 IU/mL) was found to be higher for children in Group 2 than in Group i. but both rates declined with age. Checking immunization status periodically and giving vaccine doses as required are essential to increase the antibody response. Further, it is a must in developing countries where vaccination efforts are hindered by cold-chain problems, underoptimum application practice, and high prevalence of concomitant infections.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1067/mic.2001.112687
dc.identifier.endpage123en_US
dc.identifier.issn0196-6553
dc.identifier.issue2en_US
dc.identifier.pmid11287881
dc.identifier.scopus2-s2.0-0035070890
dc.identifier.scopusqualityQ1
dc.identifier.startpage120en_US
dc.identifier.urihttps://doi.org/10.1067/mic.2001.112687
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2928
dc.identifier.volume29en_US
dc.identifier.wosWOS:000168037300011
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMosby, Incen_US
dc.relation.ispartofAmerican Journal Of Infection Control
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleTetanus IgG antibody levels in children aged 12 to 47 months in Turkeyen_US
dc.typeArticle

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