Alterations in serum biochemical parameters of patients with lung cancer exposed to radiotherapy
Yükleniyor...
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Triveni Enterprises
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, the alterations in serum biochemical parameters of patients with lung cancer exposed to radiotherapy was investigated. For this aim, the levels of serum gamma glutamyltransferase (GGT), as part ate aminotransferase (AST), alanine aminotransferase (ALT), albumin (ALB), bilurubin (BLB), copper (Cu), sodium (Na) and potassium (K) were evaluated before and after radiotherapy. Serum enzyme, protein, Na and K levels were determined using an autoanalyzer Serum Cu analysis was made with Atomic Absorbtion Spectrophotometre (AAS). Although we found significant increases in levels of GGT, BLB, Cu and Kin patients, levels of AST, ALT, ALB and Na in patients showed significant decreases. The levels of serum AST and ALT fairly decreased after radiotherapy The level of GGT in patients was significant higher than that in the controls before radiotherapy However, GGT level showed again a distinctly decrease after radiotherapy There was an inverse relationship among serum BLB, Cu and ALB values. Besides, serum Na levels showed significantly decrease in patients at the end of radiotherapy treatment compared to the controls and before radiotherapy and K levels increased significantly following radiotherapy In conclusion, the selected serum parameters are very sensitive and useful biomarkers for the study of the effects of radiotherapy
Açıklama
KURTMAN, CENGIZ/0000-0001-9865-2370
Anahtar Kelimeler
Lung cancer, Enzyme parameters, Gamma radiation, Radiotherapy, Serum elements
Kaynak
Journal Of Environmental Biology
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
31
Sayı
5
Künye
closedAccess
