Alterations in serum biochemical parameters of patients with lung cancer exposed to radiotherapy

dc.contributor.authorÇavuşoğlu, Kültigin
dc.contributor.authorArıca, Şükran Çakır
dc.contributor.authorKurtman, Cengiz
dc.date.accessioned2020-06-25T17:49:17Z
dc.date.available2020-06-25T17:49:17Z
dc.date.issued2010
dc.departmentKırıkkale Üniversitesi
dc.descriptionKURTMAN, CENGIZ/0000-0001-9865-2370
dc.description.abstractIn this study, the alterations in serum biochemical parameters of patients with lung cancer exposed to radiotherapy was investigated. For this aim, the levels of serum gamma glutamyltransferase (GGT), as part ate aminotransferase (AST), alanine aminotransferase (ALT), albumin (ALB), bilurubin (BLB), copper (Cu), sodium (Na) and potassium (K) were evaluated before and after radiotherapy. Serum enzyme, protein, Na and K levels were determined using an autoanalyzer Serum Cu analysis was made with Atomic Absorbtion Spectrophotometre (AAS). Although we found significant increases in levels of GGT, BLB, Cu and Kin patients, levels of AST, ALT, ALB and Na in patients showed significant decreases. The levels of serum AST and ALT fairly decreased after radiotherapy The level of GGT in patients was significant higher than that in the controls before radiotherapy However, GGT level showed again a distinctly decrease after radiotherapy There was an inverse relationship among serum BLB, Cu and ALB values. Besides, serum Na levels showed significantly decrease in patients at the end of radiotherapy treatment compared to the controls and before radiotherapy and K levels increased significantly following radiotherapy In conclusion, the selected serum parameters are very sensitive and useful biomarkers for the study of the effects of radiotherapyen_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage844en_US
dc.identifier.issn0254-8704
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-77956421651
dc.identifier.scopusqualityQ3
dc.identifier.startpage841en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4683
dc.identifier.volume31en_US
dc.identifier.wosWOS:000281449300016
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTriveni Enterprisesen_US
dc.relation.ispartofJournal Of Environmental Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLung canceren_US
dc.subjectEnzyme parametersen_US
dc.subjectGamma radiationen_US
dc.subjectRadiotherapyen_US
dc.subjectSerum elementsen_US
dc.titleAlterations in serum biochemical parameters of patients with lung cancer exposed to radiotherapyen_US
dc.typeArticle

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