Can cerebrospinal fluid uric acid levels differentiate intraventricular hemorrhage from traumatic tap?

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dc.contributor.authorAliefendioglu, Didem
dc.contributor.authorGürsoy, Tuğba
dc.contributor.authorHayran, K. Mutlu
dc.contributor.authorAslan, Ayşe Tana
dc.date.accessioned2020-06-25T17:41:08Z
dc.date.available2020-06-25T17:41:08Z
dc.date.issued2006
dc.departmentKırıkkale Üniversitesi
dc.descriptionAslan, Ayse Tana/0000-0002-5360-8517
dc.description.abstractObjective: To measure blood and cerebrospinal fluid (CSF) uric acid (UA) levels of neonates with intraventricular hemorrhage (IVH), and to examine whether or not UA can be used to differentiate traumatic tap from IVH. Material and Methods: The control group (n = 19, group I) consisted of neonates presenting with signs requiring analysis of CSF but whose CSF indices proved to be normal. Traumatic taps (n = 15, group II) were mimicked by adding 2 drops of homologous blood to normal CSF samples. The IVH group (n = 21, group III) consisted of neonates who had been diagnosed by cranial ultrasonography or computed tomography scans. Data are presented as median ( range). Results: There was no significant difference between groups with respect to serum UA levels. While no significant difference was observed between CSF UA levels of the control [0.6 (0.1-1.8) mg/dl] and traumatic tap group [0.5 (0.3-1.1) mg/dl], the IVH group [1.6 (0.7-6.9) mg/dl] was found to have significantly higher CSF UA levels than groups I and II. Furthermore, although there were significant correlations between serum and CSF UA levels in the control and traumatic tap groups, no correlation was observed in the IVH group. Conclusion: CSF UA levels are increased in neonates with IVH and they may be used to differentiate a real hemorrhage from a traumatic tap. Copyright (c) 2006 S. Karger AG, Basel.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1159/000094319
dc.identifier.endpage272en_US
dc.identifier.issn0006-3126
dc.identifier.issue4en_US
dc.identifier.pmid16809910
dc.identifier.scopus2-s2.0-33751167028
dc.identifier.scopusqualityN/A
dc.identifier.startpage268en_US
dc.identifier.urihttps://doi.org/10.1159/000094319
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3639
dc.identifier.volume90en_US
dc.identifier.wosWOS:000241774800010
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKargeren_US
dc.relation.ispartofBiology Of The Neonate
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecturic aciden_US
dc.subjectintraventricular hemorrhageen_US
dc.subjecttraumatic tapen_US
dc.subjectnewbornen_US
dc.titleCan cerebrospinal fluid uric acid levels differentiate intraventricular hemorrhage from traumatic tap?en_US
dc.typeArticle

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