An Investigation into the Usage of Monosaccharides with GLUT1 and GLUT3 as Prognostic Indicators for Cancer

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dc.authoridgokalp, faik/0000-0003-4363-3839
dc.contributor.authorGokalp, Faik
dc.date.accessioned2025-01-21T16:35:38Z
dc.date.available2025-01-21T16:35:38Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe monosaccharides, glucose, fructose and galactose, are the most common and simplest forms of carbohydrates. The aim of this study was to determine the uptake of glucose as a potential therapeutic target agent for cancer treatment. The stability and transportation calculations of the monosaccharides were carried out in the blood phase by using the density functional theory and docking. The reactivity of monosaccharides, disaccharides and their transportation with GLUT1 and GLUT3 as prognostic indicators for cancer were investigated. The theoretical results of this study were supported by those reported in the literature and used in the prediction of the mechanisms of monosaccharides and the interpretation of their reactivities.
dc.description.sponsorshipScientific Research Projects Department of Kirikkale University [BAP-2016/016]
dc.description.sponsorshipThis study was supported by the Scientific Research Projects Department of Kirikkale University (BAP-2016/016).
dc.identifier.doi10.1080/01635581.2021.1895233
dc.identifier.endpage519
dc.identifier.issn0163-5581
dc.identifier.issn1532-7914
dc.identifier.issue2
dc.identifier.pmid33724114
dc.identifier.scopus2-s2.0-85102848106
dc.identifier.scopusqualityQ1
dc.identifier.startpage515
dc.identifier.urihttps://doi.org/10.1080/01635581.2021.1895233
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24172
dc.identifier.volume74
dc.identifier.wosWOS:000629424100001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherRoutledge Journals, Taylor & Francis Ltd
dc.relation.ispartofNutrition and Cancer-An International Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.titleAn Investigation into the Usage of Monosaccharides with GLUT1 and GLUT3 as Prognostic Indicators for Cancer
dc.typeArticle

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