Wolff-Chaikoff effect in a newborn: is it an overlooked problem?

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dc.contributor.authorAliefendioğlu, Didem
dc.contributor.authorŞanlı, Cihat
dc.contributor.authorÇakmak, Murat
dc.contributor.authorAğar, Ayça
dc.contributor.authorAlbayrak, Meryem
dc.contributor.authorEvliyaoğlu, Olcay
dc.date.accessioned2020-06-25T15:13:36Z
dc.date.available2020-06-25T15:13:36Z
dc.date.issued2006
dc.departmentKırıkkale Üniversitesi
dc.description.abstractHypothyroidism is a serious endocrine disorder emerging from deficient production of thyroid hormone (thyroid gland agenesis or dysgenesis, or inborn metabolic defects of thyroid hormone production) or a defect in thyroid hormonal receptor activity. Prevention of iodine organification by means of using iodine-containing drugs or solutions is a protective mechanism for the body and is known as the Wolff-Chaikoff effect. This effect blocks thyroid hormone generation and is often transient, with thyroid hormone synthesis recovering in a few days or weeks. We present a neonate with transient thyroid dysfunction resulting from topical exposure to iodine-containing antiseptic solution. Our aim was to increase awareness that the use of antiseptic iodine solutions in neonates may result in transient hypothyroidism through the Wolff-Chaikoff effect and should be considered after the use of iodine-containing solutions or drugs. © 2006 Elsevier Inc. All rights reserved.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.jpedsurg.2006.08.041
dc.identifier.endpagee3en_US
dc.identifier.issn00223468
dc.identifier.issue12en_US
dc.identifier.pmid17161170
dc.identifier.scopus2-s2.0-33845213803
dc.identifier.scopusqualityQ1
dc.identifier.startpagee1en_US
dc.identifier.urihttps://doi.org/10.1016/j.jpedsurg.2006.08.041
dc.identifier.urihttps://hdl.handle.net/20.500.12587/1868
dc.identifier.volume41en_US
dc.identifier.wosWOS:000814201300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofJournal of Pediatric Surgery
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIodineen_US
dc.subjectNeonateen_US
dc.subjectTransient hypothyroidismen_US
dc.subjectWolff-Chaikoffen_US
dc.titleWolff-Chaikoff effect in a newborn: is it an overlooked problem?en_US
dc.typeArticle

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