Malondialdehyde Levels in Dental Follicles of Asymptomatic Impacted Third Molars

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dc.contributor.authorTekin, Umut
dc.contributor.authorKisa, Ucler
dc.contributor.authorGuven, Orhan
dc.contributor.authorKurku, Huseyin
dc.date.accessioned2020-06-25T17:51:52Z
dc.date.available2020-06-25T17:51:52Z
dc.date.issued2011
dc.departmentKırıkkale Üniversitesi
dc.descriptionKISA, Ucler/0000-0002-8131-6810; Kurku, Huseyin/0000-0002-1083-4151
dc.description.abstractPurpose: Increased levels of reactive oxygen species lead to oxidative stress and tissue damage. Malondialdehyde (MDA) is one of many low-molecular-weight endproducts of lipid peroxidation that increases with oxidative stress. The aim of this study was to determine oxidative stress in dental follicles (DFs) of radiologically asymptomatic impacted third molars (ITMs) using MDA. Materials and Methods: This study involved 40 DFs of 40 patients referred for clinically and radiographically asymptomatic ITMs. Forty healthy gingival tissues in the same patients were obtained during surgical removal of teeth as a control group. DF widths on periapical radiographs narrower than 2.5 mm were included in the study. All tissues samples were analyzed for MDA as an indicator of oxidative stress. Results: Levels of MDA were significantly higher in DFs from ITMs than those from healthy gingival tissues of the same patients (P < .01). Conclusion: The results suggest that significant oxidative stress may occur in DFs of asymptomatic ITMs. The findings suggest that increased MDA may play an important role in oxidative stress in DFs. In light of these preliminary findings of the present study, further investigations and comprehensive studies are required to determine the role of antioxidants that scavenge free radicals in DFs. (C) 2011 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 69:1291-1294, 2011en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.joms.2010.07.011
dc.identifier.endpage1294en_US
dc.identifier.issn0278-2391
dc.identifier.issn1531-5053
dc.identifier.issue5en_US
dc.identifier.pmid21256650
dc.identifier.startpage1291en_US
dc.identifier.urihttps://doi.org/10.1016/j.joms.2010.07.011
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5014
dc.identifier.volume69en_US
dc.identifier.wosWOS:000290242300017
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofJournal Of Oral And Maxillofacial Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleMalondialdehyde Levels in Dental Follicles of Asymptomatic Impacted Third Molarsen_US
dc.typeArticle

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