Prevalence of Pancreatic Steatosis and Its Associated Factors in Turkey: A Nation-Wide Multicenter Study

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dc.contributor.authorSezgin, Orhan
dc.contributor.authorYaras, Serkan
dc.contributor.authorCindoruk, Mehmet
dc.contributor.authorKasap, Elmas
dc.contributor.authorUnal, Hakan
dc.contributor.authorKoksal, Aydin Seref
dc.contributor.authorYildirim, Abdullah Emre
dc.date.accessioned2025-01-21T16:43:45Z
dc.date.available2025-01-21T16:43:45Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground/Aims: Pancreatic steatosis (PS) is a pathology associated with metabolic syndrome (MS), endocrin and exocrine disfunctions of the pancreas, and fatty liver. The data on the frequency of PS are very limited. We aimed to evaluate the frequency of PS detected by transabdominal ultrasonography (TAU) in gastroenterology clinics located in different geographical regions of Turkey and the factors associated with it. Materials and Methods: Volunteers were evaluated by TAU for PS and hepatosteatosis (HS), and its degree. Pancreatic stiffness was evaluated by ultrasonographic shear wave elastography (SWE). All demographic, physical, and biochemical parametres were measured. Results: A total of 1700 volunteers from 14 centers throughout Turkey were included in the study. Mean age was 48.03 +/- 20.86 years (56.9% female). Prevalance of PS was detected in 68.9%. In the PS group, age, body mass index (BMI), waist circumference, systolic blood pressure, fasting blood glucose (FBG), lipid levels, insulin resistance, diabetes mellitus, hypertension, MS frequency, and pancreatic SWE score were increasing, and fecal elastase level was decreasing in correlation with the degree of PS. The frequency of HS was 55.5%. Hepatosteatosis [odds ratio (OR): 9.472], increased age (OR: 1.02), and BMI (OR: 1.089) were independent risk factors for the occurrence of PS. Lean -PS rate was 11.8%. The lean -PS group was predominantly female and younger than non -lean PS. Also it has lower blood pressure, FBG, liver enzymes, lipid levels, and HS rates. Conclusion: The frequency of PS was found 68.9% in Turkey. Its relationship was determined with age, BMI, HS, MS (and its components), pancreatic stiffness, and fecal elastase level.
dc.identifier.doi10.5152/tjg.2024.23583
dc.identifier.issn2148-5607
dc.identifier.issue3
dc.identifier.pmid39128120
dc.identifier.scopus2-s2.0-85187943097
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.5152/tjg.2024.23583
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25313
dc.identifier.volume35
dc.identifier.wosWOS:001186228200010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAves
dc.relation.ispartofTurkish Journal of Gastroenterology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectElastography; exocrine pancreatic insufficiency; lean steatosis; pancreas stiffness; pancreatic steatosis; ultrasonography
dc.titlePrevalence of Pancreatic Steatosis and Its Associated Factors in Turkey: A Nation-Wide Multicenter Study
dc.typeArticle

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