Monitoring the metabolic response to major surgery in neonates.
[ X ]
Tarih
2000
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
BACKGROUND: Visceral proteins and acute phase reactants have commonly been used as indicators of nutritional status, and metabolic response of surgical trauma. AIM: This study was undertaken to determine how some plasma proteins, alone or together reflect metabolic response in neonates recovering from major surgery. METHODS: Serum albumin, pre-albumin (PA), C-reactive protein (CRP), and alpha1-acid glycoprotein (AGP) levels were measured, and the prognostic inflammatory and nutritional index (PINI) was calculated for preoperative day 1 (-1) and postoperative (PO) days 1 (+1) and 7 (+7). RESULTS: PA, CRP, AGP and PINI were significantly different on day +1 from day -1. While AGP and PINI were still significantly higher than that of day -1, PA and CRP returned to the preoperative levels on day +7. CONCLUSION: PA, CRP and AGP measurements are superior to PINI for assessing postoperative metabolic changes in term neonates following uncomplicated major surgery on early and late phase. But this comparison must be performed in the management of more complex cases to determine which one is better to indicate morbidity and mortality.
Açıklama
Anahtar Kelimeler
Kaynak
International journal of surgical investigation
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
2
Sayı
4
