Monitoring the metabolic response to major surgery in neonates.

dc.contributor.authorCaglayan F.
dc.contributor.authorCaglayan O.
dc.contributor.authorGunel E.
dc.contributor.authorSahin T.K.
dc.date.accessioned2020-06-25T15:13:11Z
dc.date.available2020-06-25T15:13:11Z
dc.date.issued2000
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBACKGROUND: Visceral proteins and acute phase reactants have commonly been used as indicators of nutritional status, and metabolic response of surgical trauma. AIM: This study was undertaken to determine how some plasma proteins, alone or together reflect metabolic response in neonates recovering from major surgery. METHODS: Serum albumin, pre-albumin (PA), C-reactive protein (CRP), and alpha1-acid glycoprotein (AGP) levels were measured, and the prognostic inflammatory and nutritional index (PINI) was calculated for preoperative day 1 (-1) and postoperative (PO) days 1 (+1) and 7 (+7). RESULTS: PA, CRP, AGP and PINI were significantly different on day +1 from day -1. While AGP and PINI were still significantly higher than that of day -1, PA and CRP returned to the preoperative levels on day +7. CONCLUSION: PA, CRP and AGP measurements are superior to PINI for assessing postoperative metabolic changes in term neonates following uncomplicated major surgery on early and late phase. But this comparison must be performed in the management of more complex cases to determine which one is better to indicate morbidity and mortality.en_US
dc.identifier.endpage312en_US
dc.identifier.issn10285229
dc.identifier.issue4en_US
dc.identifier.pmid12678533
dc.identifier.scopus2-s2.0-0038823891
dc.identifier.scopusqualityN/A
dc.identifier.startpage309en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/1645
dc.identifier.volume2en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofInternational journal of surgical investigation
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleMonitoring the metabolic response to major surgery in neonates.en_US
dc.typeArticle

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