Evaluation of adrenomedullin and endothelin-1: Are they factors in the adaptation of maternal vascular system in normotensive pregnancy

Basit Öğe Kaydı
dc.contributor.authorBayram, Merih
dc.contributor.authorBostanci, Suhha
dc.contributor.authorCaglayan, Osman
dc.contributor.authorIlhan, Mustafa N.
dc.date.accessioned2020-06-25T17:44:45Z
dc.date.available2020-06-25T17:44:45Z
dc.date.issued2008
dc.description.abstractIntroduction: The aim of our study was to analyse the role of adrenomedullin (AM) and endothelin-1 (ET-1) in the adaptation of the maternal vascular system in normotensive pregnancy. Methods: Twenty-eight pregnant women, who were normotensive throughout the duration of their pregnancy, were recruited into the study. Plasma levels of AM and ET-1 at each trimester were measured and the AM/ET-1 ratio was calculated. Results: Our experiment showed a significant decrease in plasma concentrations of AM in the first trimester for the study group (n=28) compared with the non-pregnant control group (n=16). There was also a significant decrease in plasma concentrations of ET-1 in all three trimesters (P < 0.05) and a significant increase in the AM/ET-1 ratio in all three trimesters (P < 0.05) for the study group compared with the control group. Conclusion: An alteration in vascular equilibrium between AM and ET-1, favouring AM, may be a reason why the physiological adaptation of the maternal vascular system to pregnancy occurs during normotensive pregnancy.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1007/s12325-008-0041-y
dc.identifier.endpage374en_US
dc.identifier.issn0741-238X
dc.identifier.issn1865-8652
dc.identifier.issue4en_US
dc.identifier.pmid18463805
dc.identifier.scopus2-s2.0-58149327334
dc.identifier.scopusqualityQ1
dc.identifier.startpage367en_US
dc.identifier.urihttps://doi.org10.1007/s12325-008-0041-y
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4185
dc.identifier.volume25en_US
dc.identifier.wosWOS:000255873700007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringeren_US
dc.relation.ispartofAdvances In Therapy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectadrenomedullinen_US
dc.subjectadrenomedullin/endothelin-1 ratioen_US
dc.subjectendothelin-1en_US
dc.subjectpregnancyen_US
dc.subjectthree trimestersen_US
dc.titleEvaluation of adrenomedullin and endothelin-1: Are they factors in the adaptation of maternal vascular system in normotensive pregnancyen_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Evaluation of adrenomedullin and endothelin-1 Are they factors in the adaptation of maternal vascular system in normotensive pregnancy.pdf
Boyut:
186.79 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu