The effects of darkness on retrobulbar hemodynamics in patients with early stages retinitis pigmentosa
Yükleniyor...
Tarih
2004
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: To investigate the retrobulbar hemodynamic changes occurring in light and darkness in patients with early stages retinitis pigmentosa (RP). Methods: Eleven early stages RP patients were enrolled in the study. The peak systolic velocity (PSV), end-diastolic velocity (EDV), pulsatility index (PI) and resistivity index (RI) of the ophthalmic artery (OA) and central retinal artery (CRA) were measured by color Doppler imaging in light and darkness. The results were compared with that of 10 age-matched normal subjects. Results: PSV and EDV of the OA did not show significant differences in both groups. However, PSV and EDV of the CRA in RP patients decreased significantly in darkness (p = 0.001, p < 0.001, respectively). In addition, we found a significant increase in RI of the CRA in RP patients in darkness (p = 0.003). On the contrary, PSV and EDV of the CRA in control subjects showed a significant increase (p = 0.002, p < 0.001, respectively) and RI showed a significant decrease in darkness (p = 0.004). Conclusions: Darkness causes a decreased blood flow in the CRA in early stages of RP. © 2004 Kluwer Academic Publishers.
Açıklama
Anahtar Kelimeler
Color doppler imaging, Darkness, Retinitis pigmentosa
Kaynak
International Ophthalmology
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
25
Sayı
2
Künye
closedAccess
