The effects of darkness on retrobulbar hemodynamics in patients with early stages retinitis pigmentosa

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dc.contributor.authorTaner, Pelin
dc.contributor.authorKara, Simay A.
dc.contributor.authorAkarsu, Cengiz
dc.contributor.authorErgin, Ahmet
dc.date.accessioned2020-06-25T15:13:25Z
dc.date.available2020-06-25T15:13:25Z
dc.date.issued2004
dc.departmentKırıkkale Üniversitesi
dc.description.abstractPurpose: To investigate the retrobulbar hemodynamic changes occurring in light and darkness in patients with early stages retinitis pigmentosa (RP). Methods: Eleven early stages RP patients were enrolled in the study. The peak systolic velocity (PSV), end-diastolic velocity (EDV), pulsatility index (PI) and resistivity index (RI) of the ophthalmic artery (OA) and central retinal artery (CRA) were measured by color Doppler imaging in light and darkness. The results were compared with that of 10 age-matched normal subjects. Results: PSV and EDV of the OA did not show significant differences in both groups. However, PSV and EDV of the CRA in RP patients decreased significantly in darkness (p = 0.001, p < 0.001, respectively). In addition, we found a significant increase in RI of the CRA in RP patients in darkness (p = 0.003). On the contrary, PSV and EDV of the CRA in control subjects showed a significant increase (p = 0.002, p < 0.001, respectively) and RI showed a significant decrease in darkness (p = 0.004). Conclusions: Darkness causes a decreased blood flow in the CRA in early stages of RP. © 2004 Kluwer Academic Publishers.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1023/B:INTE.0000031743.67336.b5
dc.identifier.endpage99en_US
dc.identifier.issn01655701
dc.identifier.issue2en_US
dc.identifier.pmid15290888
dc.identifier.scopus2-s2.0-3042523860
dc.identifier.scopusqualityQ2
dc.identifier.startpage95en_US
dc.identifier.urihttps://doi.org/10.1023/B:INTE.0000031743.67336.b5
dc.identifier.urihttps://hdl.handle.net/20.500.12587/1783
dc.identifier.volume25en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofInternational Ophthalmology
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectColor doppler imagingen_US
dc.subjectDarknessen_US
dc.subjectRetinitis pigmentosaen_US
dc.titleThe effects of darkness on retrobulbar hemodynamics in patients with early stages retinitis pigmentosaen_US
dc.typeArticle

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