The effective natural compounds for inhibiting Cervical cancer

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dc.authoridgokalp, faik/0000-0003-4363-3839
dc.contributor.authorGokalp, Faik
dc.date.accessioned2025-01-21T16:45:22Z
dc.date.available2025-01-21T16:45:22Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe secondary compounds found in plants are of great importance in the treatment of many diseases in medicine and pharmacy. Some of these compounds have been reported to exhibit anticarcinogenic effects by inhibiting the growth and metastatic potential of cancer cells. Consumption of the required amount of vegetables and fruits appears to have a protective effect of these secondary compounds on cancer, since most of these drugs are synthesized from natural or natural origin compounds. Secondary compounds in medicinal plants have been found to have an antiproliferative effect by increasing the expression of p53 in cervical cancer cells and decreasing the expression of cyclin D1, one of the cell proliferation markers. The most important step in the fight against cancer is the development of drugs that are selectively targeted against tumor cells and targeting cancer cells to reduce damage to normal cells and prevent the growth and spread of cancer cells. Molecular insertion test is an effective tool for evaluating the bioactivity of possible molecules. In this study, the effect of natural compounds in some medicinal plants in inhibiting cervical cancer, the points where they are effective using docking has been investigated.
dc.description.sponsorshipKirikkale University
dc.description.sponsorshipThe study of the author was supported by Kirikkale University.
dc.identifier.doi10.1007/s12032-021-01456-3
dc.identifier.issn1357-0560
dc.identifier.issn1559-131X
dc.identifier.issue2
dc.identifier.pmid33474656
dc.identifier.scopus2-s2.0-85099816549
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1007/s12032-021-01456-3
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25628
dc.identifier.volume38
dc.identifier.wosWOS:000609173100001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHumana Press Inc
dc.relation.ispartofMedical Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectP53 carcinoma cell; Docking; Thymol; Carvacrol; Tymoquinone
dc.titleThe effective natural compounds for inhibiting Cervical cancer
dc.typeArticle

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