High-Dose Ropivacaine versus Bupivacaine for Posttonsillectomy Pain Relief in Adults

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dc.contributor.authorArikan, Osman Kursat
dc.contributor.authorŞahin, Saziye
dc.contributor.authorKazkayasi, Mustafa
dc.contributor.authorMuluk, Nuray Bayar
dc.contributor.authorAkpinar, Serpil
dc.contributor.authorKilic, Rahmi
dc.date.accessioned2020-06-25T17:44:14Z
dc.date.available2020-06-25T17:44:14Z
dc.date.issued2008
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: To compare the efficacy and safety of preincisional high-dose ropivacaine with bupivacaine in relieving posttonsillectomy pain. Design: A prospective, randomized, double blind, placebo-controlled clinical trial. Setting: University hospital. Patients: Before the incision, 58 subjects were randomly assigned to receive 10 mL of 10 mg/mL ropivacaine hydrochloride with epinephrine (n = 19, group 1), 10 mL of 2.5 mg/mL bupivacaine with epinephrine (n = 20, group 2), or saline with epinephrine (n = 19, group 3) as a placebo. Main Outcomes Measures: Postoperative pain, additional analgesic drug consumption, otalgia, operating time, amount of intraoperative blood loss, and possible complications were assessed. The intensity of pain was scored on a visual analogue scale. The patients were followed up for 10 days after surgery. Results: There were no statistically significant differences between the demographic and operational characteristics of the patient groups. Statistically significant differences were determined between in the mean intensity of constant and swallowing pain values of group 1 and group 2 or 3, at 4, 8, and 12 hours, and on days 1, 2, 3, and 4, postoperatively. However, no statistical differences were determined between the groups on days 5, 7, and 10. A lower amount of additional analgesic drug was consumed by the ropivacaine group than by the bupivacaine group, and by the bupivacaine group than by the control group, and the differences were statistically significant. Conclusion: Preincisional infiltration of the tonsils with high-dose ropivacaine markedly decreased the intensity of pain after tonsillectomy when compared with bupivacaine or placebo, especially until postoperative day 4 in adults.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.2310/7070.2008.OA0189
dc.identifier.endpage843en_US
dc.identifier.issn1916-0216
dc.identifier.issue6en_US
dc.identifier.pmid19128713
dc.identifier.scopus2-s2.0-64349103842
dc.identifier.scopusqualityQ1
dc.identifier.startpage836en_US
dc.identifier.urihttps://doi.org/10.2310/7070.2008.OA0189
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4049
dc.identifier.volume37en_US
dc.identifier.wosWOS:000207463500026
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBmcen_US
dc.relation.ispartofJournal Of Otolaryngology-Head & Neck Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbupivacaineen_US
dc.subjecthigh-dose ropivacaineen_US
dc.subjectposttonsillectomy painen_US
dc.titleHigh-Dose Ropivacaine versus Bupivacaine for Posttonsillectomy Pain Relief in Adultsen_US
dc.typeArticle

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