Preincisional infiltration of tonsils with ropivacaine in post-tonsillectomy pain relief: double-blind, randomized, placebo-controlled intraindividual study

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dc.contributor.authorArıkan, Osman Kürşat
dc.contributor.authorÖzcan, Şaziye
dc.contributor.authorKazkayasi, Mustafa
dc.contributor.authorAkpinar, Serpil
dc.contributor.authorKoç, Can
dc.date.accessioned2020-06-25T17:43:32Z
dc.date.available2020-06-25T17:43:32Z
dc.date.issued2006
dc.description.abstractObjective: To determine whether pre-emptive ropivacaine has an influence on postoperative pain in adult patients undergoing tonsillectomy. Design: A prospective, randomized, double-blind, placebo-controlled clinical trial. Setting: University hospital. Patients: The study included 20 adult patients undergoing elective tonsillectomy. Anesthetic induction and maintenance, dissection tonsillectomy, hemostasis techniques, and postoperative analgesic treatment were standardized for all patients. Before the onset of incision, one tonsillar fossa was administered 5 mL of 2% ropivacaine hydrochloride with epinephrine, whereas the other side received 5 mL of 0.9% saline with epinephrine and was designated as the control side. Main Outcomes Measures: For each side, postoperative pain, otalgia, operating time, amount of intraoperative blood loss, and postoperative hemorrhage were assessed. The intensity of postoperative pain was measured at rest and when the patient was drinking and was scored on a visual analogue scale. The patients were followed up for 10 days after surgery. Results: There was no statistically significant difference in the amount of intraoperative hemorrhage and operation time between sides (p >.05). The constant postoperative pain in the ropivacaine side at rest was significantly less than in the placebo side on days 1, 2, 5, and 6 (p <.05). The post-tonsillectomy pain experienced in the ropivacaine side when swallowing was significantly less than that in the placebo side throughout the study period except on day 10 (p <.05). Conclusion: Based on the present findings, preincisional infiltration of ropivacaine 2% appears to be effective against both early and late postoperative pain, especially on swallowing, following tonsillectomy in adults.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.2310/7070.2005.0029
dc.identifier.endpage172en_US
dc.identifier.issn0381-6605
dc.identifier.issue3en_US
dc.identifier.pmid16929992
dc.identifier.scopus2-s2.0-33745190688
dc.identifier.scopusqualityN/A
dc.identifier.startpage167en_US
dc.identifier.urihttps://doi.org10.2310/7070.2005.0029
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3778
dc.identifier.volume35en_US
dc.identifier.wosWOS:000238166800003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherB C Decker Incen_US
dc.relation.ispartofJournal Of Otolaryngology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpostoperative painen_US
dc.subjectropivacaineen_US
dc.subjecttonsillectomyen_US
dc.titlePreincisional infiltration of tonsils with ropivacaine in post-tonsillectomy pain relief: double-blind, randomized, placebo-controlled intraindividual studyen_US
dc.typeArticle

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