Effect of hyaluronic acid on the osseointegration of dental implants
Yükleniyor...
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Churchill Livingstone
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The mechanism of osseointegration is related to many factors, including the quality of the bone, the biocompatibility and surface characteristics of the implant material, the surgical technique, and functional loading. The purpose of this study was to investigate the effects of hyaluronic acid gel on the osseointegration of implants placed in defined areas of the mandible in rabbits. Hyaluronic acid is known to have an osteoinductive effect during regeneration of bony defects, and we thought that it might also have a favourable effect on osseointegration, a specialised mechanism to heal bone. Ten New Zealand rabbits aged 10 weeks and weighing 2.5-3.0 kg were used, and sites for implants that were far enough from the apices of the teeth in the mandibular molar area were chosen. Two cavities were prepared in each rabbit, one (anterior) for the control implant, and one (posterior) for the implant with hyaluronic acid gel (Medical Instinct GmbH, Bovenden). New bone and the osteoid matrix content around the dental implants were evaluated histologically and histomorphometrically two months after the operation, and no significant difference was found between the two groups. (C) 2018 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
Açıklama
yazan, murude/0000-0003-0618-9070; Onder, M Ercument/0000-0002-1488-616X; ATIL, Fethi/0000-0002-8286-4819
Anahtar Kelimeler
Hyaluronic acid, Dental implant, Osseointegration, Rabbit Mandible, Histopathology, Bone Repairing
Kaynak
British Journal Of Oral & Maxillofacial Surgery
WoS Q Değeri
Q4
Scopus Q Değeri
Q1
Cilt
57
Sayı
1
Künye
closedAccess
