Effect of 23 valent pneumococcal polysaccharide and Haemophilus influenza conjugated vaccines on the clinical course of otitis media with effusion

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dc.contributor.authorKılıc, R.
dc.contributor.authorŞafak, M.A.
dc.contributor.authorÖzdek, A.
dc.contributor.authorGöçmen, H.
dc.contributor.authorKılıç, D.
dc.contributor.authorSamim, E.
dc.date.accessioned2020-06-25T17:34:58Z
dc.date.available2020-06-25T17:34:58Z
dc.date.issued2002
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective. To determine if there is any clinical effect of 23-valent pneumococcal and Haemophilus influenza type B conjugate vaccine on prognosis of otitis media with effusion. Method: All children who have middle ear effusion despite long-standing antibiotherapy with a beta lactamase stable agent were offered for tympanostomy tube insertion between February 1999 and December 2001. Patients who accepted the surgical intervention were operated under general anesthesia and a Shepard grommet-type tympanostomy tube was inserted. Those who refused the surgical intervention were vaccinated with 23-valent pneumococcal and Haemophilus influenza type B conjugate vaccine. State of the middle ear effusion was evaluated at the end of the 12th month in the vaccine group and 1 month after the myringotomy site was healed in the tympanostomy tube insertion group. Results: Twenty-six children in the vaccine group and 37 children in the tympanostomy tube insertion group proved the inclusion criteria at the end of study. Complete or partial resolution of middle ear effusion was observed in 73.1% of 26 children in the vaccine group and 59.5% of children in the tympanostomy tube insertion group. There was no significant difference between the two groups. Conclusion: Vaccination against Streptococcus pneumonia and Haemophilus influenza type b seems to aid resolution of middle ear effusion in children with otitis media with effusion.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1097/00005537-200211000-00024
dc.identifier.endpage2045en_US
dc.identifier.issn0023-852X
dc.identifier.issn1531-4995
dc.identifier.issue11en_US
dc.identifier.pmid12439177
dc.identifier.scopus2-s2.0-0036842520
dc.identifier.scopusqualityQ1
dc.identifier.startpage2042en_US
dc.identifier.urihttps://doi.org/10.1097/00005537-200211000-00024
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2970
dc.identifier.volume112en_US
dc.identifier.wosWOS:000179193300024
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWileyen_US
dc.relation.ispartofLaryngoscope
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject23-valent pneumococcal vaccineen_US
dc.subjectHaemophilus influenza type b conjugate vaccineen_US
dc.subjectotitis media with effusionen_US
dc.titleEffect of 23 valent pneumococcal polysaccharide and Haemophilus influenza conjugated vaccines on the clinical course of otitis media with effusionen_US
dc.typeArticle

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