Vitamin D levels in children with COVID-19: a report from Turkey

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dc.contributor.authorAlpcan, Aysegul
dc.contributor.authorTursun, Serkan
dc.contributor.authorKandur, Yasar
dc.date.accessioned2025-01-21T16:55:53Z
dc.date.available2025-01-21T16:55:53Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractSeveral studies have demonstrated that higher levels of vitamin D are associated with better prognosis and outcomes in infectious diseases. We aimed to compare the vitamin D levels of paediatric patients with mild/moderate coronavirus disease 2019 (COVID-19) disease and a healthy control group. We retrospectively reviewed the medical records of patients who were hospitalised at our university hospital with the diagnosis of COVID-19 during the period between 25 May 2020 and 24 December 2020. The mean age of the COVID-19 patients was 10.7 +/- 5.5 years (range 1-18 years); 43 (57.3%) COVID-19 patients were male. The mean serum vitamin D level was significantly lower in the COVID-19 group than the control group (21.5 +/- 10.0 vs. 28.0 +/- 11.0 IU, P < 0.001). The proportion of patients with vitamin D deficiency was significantly higher in the COVID-19 group than the control group (44% vs. 17.5%, P < 0.001). Patients with low vitamin D levels were older than the patients with normal vitamin D levels (11.6 +/- 4.9 vs. 6.2 +/- 1.8 years, P = 0.016). There was a significant male preponderance in the normal vitamin D group compared with the low vitamin D group (91.7% vs. 50.8%, P = 0.03). C-reactive protein level was higher in the low vitamin D group, although the difference did not reach statistical significance (9.6 +/- 2.2 vs. 4.5 +/- 1.6 mg/l, P = 0.074). Our study provides an insight into the relationship between vitamin D deficiency and COVID-19 for future studies. Empiric intervention with vitamin D can be justified by low serum vitamin D levels.
dc.identifier.doi10.1017/S0950268821001825
dc.identifier.issn0950-2688
dc.identifier.issn1469-4409
dc.identifier.pmid34375576
dc.identifier.scopus2-s2.0-85113835254
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1017/S0950268821001825
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25866
dc.identifier.volume149
dc.identifier.wosWOS:000683532200001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCambridge Univ Press
dc.relation.ispartofEpidemiology and Infection
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectChildren; COVID-19; vitamin D
dc.titleVitamin D levels in children with COVID-19: a report from Turkey
dc.typeArticle

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