Effect of intracanal diode laser application and low-level laser therapy on CGRP change

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dc.contributor.authorArslan, Hakan
dc.contributor.authorKoseoglu, Serhat
dc.contributor.authorDoganay Yildiz, Ezgi
dc.contributor.authorArabaci, Taner
dc.contributor.authorSavran, Levent
dc.contributor.authorYildiz, Dursun Anil
dc.contributor.authorVeyisoglu, Gozde
dc.date.accessioned2020-06-25T18:29:47Z
dc.date.available2020-06-25T18:29:47Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.descriptionSavran, Levent/0000-0001-8824-3207
dc.description.abstractThe aim of this study was to investigate the effect of a placebo, intracanal diode laser application, and low-level laser therapy (LLLT) on the change of the total amount of calcitonin gene-related peptide (CGRP) in the gingival crevicular fluid (GCF) (split-mouth study design). GCF sampling was performed on a contralateral tooth and experimental tooth (root canal-treated tooth) of thirty-nine patients. The patients were divided into three groups (n = 13), as follows: placebo (mock laser application), intracanal laser application, and LLLT. GCF sampling was repeated at the same sites (experimental and control teeth) one week after root canal treatment. The data were analyzed using the Pearson's correlation analysis and the independent-samples t-tests (p=0.05). In the placebo group, the total CGRP level changes in the GCF before and after treatment was significantly higher for experimental teeth than for control teeth (p<0.05). However, there was no significant difference between experimental and control teeth in the intracanal laser application and LLLT groups (p > 0.05). Intracanal laser application and low-level laser therapy have immunomodulation effects linked to the modulation of the total amount of CGRP in the GCF.en_US
dc.identifier.citationArslan, Hakan & Köseoğlu, Serhat & Doganay Yıldız, Ezgi & Arabacı, Taner & Sarvan, Levent & Yildiz, Dursun & Veyisoğlu, Gözde. (2019). Effect of intracanal diode laser application and low-level laser therapy on CGRP change. Brazilian Oral Research. 32. 10.1590/1807-3107bor-2018.vol32.0125.en_US
dc.identifier.doi10.1590/1807-3107bor-2018.vol32.0125
dc.identifier.issn1807-3107
dc.identifier.pmid30892373
dc.identifier.scopus2-s2.0-85063271424
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1590/1807-3107bor-2018.vol32.0125
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7457
dc.identifier.volume32en_US
dc.identifier.wosWOS:000467760500026
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSociedade Brasileira De Pesquisa Odontologicaen_US
dc.relation.ispartofBrazilian Oral Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCalcitonin Gene-Related Peptideen_US
dc.subjectLasersen_US
dc.subjectGingival Crevicular Fluiden_US
dc.subjectLow-Level Laser Therapyen_US
dc.titleEffect of intracanal diode laser application and low-level laser therapy on CGRP changeen_US
dc.typeArticle

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