Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings
Yükleniyor...
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmada; K vitamini eksikliğine bağlı intrakraniyal kanaması olan 25 infantın klinik, radyolojik bulguları ve risk faktörleri geriye dönük olarak değerlendirildi. 25 olgunun 2 (%8)'si klasik tip ve 23'ü geç başlangıçlı tipte idi. 18 (%72)'i erkek ve 7 (%28)'si kız idi. Olguların 24 (%96)'ü sadece anne sütü ile beslenmekteydi. Olguların 18'ine doğumdan sonra K vitamini uygulanmıştı. En fazla görülen semptom kusma (%44) ve konvülsiyon (%40) idi. En fazla saptanan muayene bulgusu fontanel bombeliği (%40) ve solukluk (%40) idi. Onbir (%44) hastada intrakraniyal kanama birden fazla bölgede vardı ve kanama en fazla (%68) intraparankimal alana olmuştu. 12 olgu izleminde normal mental-motor gelişim gösterirken, mortalite oranı %8 bulundu. İntrakraniyal kanama özellikle geç tipin bulgusu olup en fazla intraparankimal alanda olmaktadır. Anne sütü ile beslenen bebeklerde doğumdan sonra K vitaminin yapılmamış olması en önemli risk faktörüdür.
This retrospective study presents clinical and radiological findings and outcomes of 25 infants with intracranial hemorrhage due to vitamin K deficiency and evaluates the risk factors. Two of the infants (8%) were classical type and the others were late onset. Of the patients, 18 (72%) were male and 7 (28%) were female. Twenty four infants (96%) were being fed exclusively on breast milk. Eighteen of them (72%) had not received vitamin K prophylaxis at birth. The most disabling clinical symptoms were vomiting (44%) and convulsions (40%). The most common presentations were bulging fontanel (40%) and paleness (40%). Eleven patients (44%) showed intracranial hemorrhages at more than one site. Intraparenchymal hemorrhage was the commonest (68%) type of hemorrhage. Twelve of cases (57%) were developmentally normal. Mortality rate was 8%. Late type is frequently associated with intracranial hemorrhage particularly intraparenchymal. Lack of administration of vitamin K at birth to breastfeed babies is the most important risk factor for intracranial hemorrhage.
This retrospective study presents clinical and radiological findings and outcomes of 25 infants with intracranial hemorrhage due to vitamin K deficiency and evaluates the risk factors. Two of the infants (8%) were classical type and the others were late onset. Of the patients, 18 (72%) were male and 7 (28%) were female. Twenty four infants (96%) were being fed exclusively on breast milk. Eighteen of them (72%) had not received vitamin K prophylaxis at birth. The most disabling clinical symptoms were vomiting (44%) and convulsions (40%). The most common presentations were bulging fontanel (40%) and paleness (40%). Eleven patients (44%) showed intracranial hemorrhages at more than one site. Intraparenchymal hemorrhage was the commonest (68%) type of hemorrhage. Twelve of cases (57%) were developmentally normal. Mortality rate was 8%. Late type is frequently associated with intracranial hemorrhage particularly intraparenchymal. Lack of administration of vitamin K at birth to breastfeed babies is the most important risk factor for intracranial hemorrhage.
Açıklama
Anahtar Kelimeler
Nörolojik Bilimler
Kaynak
Journal of Neurological Sciences (Turkish)
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
26
Sayı
1
Künye
Mısırlıoğlu E. D., Aliefendioğlu D., Bademci G., Baydar Z., Köse G., Çakmak F. N. (2009). Intracranial hemorrhage due to vitamin K deficiency in ınfancy: Clinical and radiological findings. Journal of Neurological Sciences (Turkish), 26(1), 18 - 25.
