The effects of hormone replacement therapy on ocular surface and tear function tests in postmenopausal women

Basit Öğe Kaydı
dc.contributor.authorTaner, P
dc.contributor.authorAkarsu, C
dc.contributor.authorAtasoy, P
dc.contributor.authorBayram, M
dc.contributor.authorErgin, A
dc.date.accessioned2020-06-25T17:40:14Z
dc.date.available2020-06-25T17:40:14Z
dc.date.issued2004
dc.departmentKırıkkale Üniversitesi
dc.description.abstractPurpose: To prospectively investigate the impact of various hormone replacement therapies (HRT) on ocular surface and tear function tests. Methods: A total of 70 women in the postmenopausal period were enrolled in the study. The groups consisted of 16 women who were not on HRT ( group 1), 29 women who were on HRT with tibolone ( group 2) and 25 women who received estradiol plus medroxyprogesterone acetate treatment ( group 3). All patients underwent tear film break-up time (TF-BUT), Schirmer's test and conjunctiva cytology at the time of enrollment and at 6 months' follow-up. Results: Patients in group 2 showed improved Schirmer's test and TFBUT results (p < 0.001); however, no significant changes occurred in group 1 and group 3 patients (p > 0.05). Conjunctival cytology scores did not differ at the time of enrollment and at 6 months' follow-up in all groups. Conclusions: This is the first comparative clinical study on the effects of tibolone and estradiol plus medroxyprogesterone acetate on ocular surface and tear function tests. HRT with tibolone seems to improve tear function tests in postmenopausal women. Copyright (C) 2004 S. Karger AG, Basel.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1159/000078616
dc.identifier.endpage259en_US
dc.identifier.issn0030-3755
dc.identifier.issue4en_US
dc.identifier.pmid15258414
dc.identifier.scopus2-s2.0-3242811390
dc.identifier.scopusqualityQ1
dc.identifier.startpage257en_US
dc.identifier.urihttps://doi.org/10.1159/000078616
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3356
dc.identifier.volume218en_US
dc.identifier.wosWOS:000222602100005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKargeren_US
dc.relation.ispartofOphthalmologica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmenopauseen_US
dc.subjectdry eye syndromeen_US
dc.subjecthormone replacementen_US
dc.subjectconjunctival cytologyen_US
dc.subjecttiboloneen_US
dc.titleThe effects of hormone replacement therapy on ocular surface and tear function tests in postmenopausal womenen_US
dc.typeArticle

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