The prevalence and diagnostic criteria of health-care associated infections in neonatal intensive care units in Turkey: A multicenter point- prevalence study

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dc.authoridCakir, Salih Cagri/0000-0001-5761-4757
dc.authoridunal, sezin/0000-0002-5124-4422
dc.authoridGursoy, Tugba/0000-0002-6084-4067
dc.authoridUygun, Saime Sundus/0000-0002-6694-8115
dc.authoridBeken, Serdar/0000-0002-8609-2684
dc.authoridEcevit, Ayse/0000-0002-2232-8117
dc.authoridUnal, Sevim/0000-0002-7863-1924
dc.contributor.authorDemirdag, Tugba Bedir
dc.contributor.authorKoc, Esin
dc.contributor.authorTezer, Hasan
dc.contributor.authorOguz, Suna
dc.contributor.authorSatar, Mehmet
dc.contributor.authorSaglam, Ozge
dc.contributor.authorUygun, Saime Sunduz
dc.date.accessioned2025-01-21T16:55:11Z
dc.date.available2025-01-21T16:55:11Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: Healthcare-acquired infections (HAIs) in the neonatal period cause substantial morbidity, mortality, and healthcare costs. Our purpose was to determine the prevalence of HAIs, antimicrobial susceptibility of causative agents, and the adaptivity of the Centres for Disease Control and Prevention (CDC) criteria in neonatal HAI diagnosis. Methods: A HAI point prevalence survey was conducted in the neonatal intensive care units (NICUs) of 31 hospitals from different geographic regions in Turkey. Results: The Point HAI prevalence was 7.6%. Ventilator-associated pneumonia (VAP) and central line-associated bloodstream infections (CLABSI) and late onset sepsis were predominant. The point prevalence of VAP was 2.1%, and the point prevalence of CLABSI was 1.2% in our study. The most common causative agents in HAIs were Gram-negative rods (43.0%), and the most common agent was Klebsiella spp (24.6%); 81.2% of these species were extended spectrum beta-lactamase (ESBL) (& thorn;). Blood culture positivity was seen in 33.3% of samples taken from the umbilical venous catheter, whereas 0.9% of samples of peripherally inserted central catheters (PICCs) were positive. In our study, 60% of patients who had culture positivity in endotracheal aspirate or who had purulent endotracheal secretions did not have any daily FiO2 change (p = 0.67) and also 80% did not have any increase in positive end-expiratory pressure (PEEP) (p = 0.7). On the other hand, 18.1% of patients who had clinical deterioration compatible with VAP did not have endotracheal culture positivity (p = 0.005). Conclusions: Neonatal HAIs are frequent adverse events in district and regional hospitals. This at-risk population should be prioritized for HAI surveillance and prevention programs through improved infection prevention practices, and hand hygiene compliance should be conducted. CDC diagnostic criteria are not sufficient for NICUs. Future studies are warranted for the diagnosis of HAIs in NICUs.
dc.identifier.doi10.1016/j.pedneo.2021.01.001
dc.identifier.endpage217
dc.identifier.issn1875-9572
dc.identifier.issn2212-1692
dc.identifier.issue2
dc.identifier.pmid33546932
dc.identifier.scopus2-s2.0-85100414539
dc.identifier.scopusqualityQ2
dc.identifier.startpage208
dc.identifier.urihttps://doi.org/10.1016/j.pedneo.2021.01.001
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25718
dc.identifier.volume62
dc.identifier.wosWOS:000631823700012
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Taiwan
dc.relation.ispartofPediatrics and Neonatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjecthealth-care associated infection; neonate; point prevalence; surveillance
dc.titleThe prevalence and diagnostic criteria of health-care associated infections in neonatal intensive care units in Turkey: A multicenter point- prevalence study
dc.typeArticle

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