Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study

Basit Öğe Kaydı
dc.contributor.authorAtılgan, Remzi
dc.contributor.authorPala, Şehmus
dc.contributor.authorKuloğlu, Tuncay
dc.contributor.authorŞanlı, Cengiz
dc.contributor.authorYavuzkır, Şeyda
dc.contributor.authorÖzkan, Zehra
dc.date.accessioned2021-01-14T18:16:49Z
dc.date.available2021-01-14T18:16:49Z
dc.date.issued2020
dc.description.abstractBackground and aim: To compare the effects of bilateral proximal tubal occlusion and bilateral total salpingectomy on ovarian reserve and the cholinergic system via rat experiment. Materials and methods: Twenty-one adult female rats were randomly divided into the following three groups: G1 (n = 7), sham group; G2 (n = 7), bilateral total salpingectomy group; and G3 (n = 7), bilateral proximal tubal occlusion group. Four weeks later, the abdomen of the rats was opened. The right ovarian tissues were stored in 10% formaldehyde, whereas the left ovarian tissues were stored at –80 °C in aluminum foil. Serum samples were evaluated for antimullerian hormone. The right ovary was used for histological and immunoreactive examination, and the left ovary was used for tissue MDA analysis. Tissue samples were analyzed for MDA levels with spectrophotometric measurement, apoptosis with TUNEL staining, fibrosis score with Mason trichrome staining, ovarian reserve with HE staining, and cholinergic receptor muscarinic 1 (CHRM1) level with immunoreactivity method. Results: Compared to G1 and G3, the number of corpus luteum with secondary follicles was significantly lower in G2, whereas the number of ovarian cysts and fibrosis and apoptosis scores increased significantly. The CHRM1 immunoreactivity was significantly lower in G2 than in G1 and G3. Conclusions: Compared to the bilateral proximal tubal occlusion performed by using bipolar cautery, bilateral total salpingectomy in rats leads to a significant damage in ovarian histopathology and the cholinergic system.en_US
dc.identifier.citationAtılgan, R., Pala, Ş., Kuloğlu, T., Şanlı, C., Yavuzkır, Ş., Özkan, Z. (2020). Comparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental study. Turkish Journal of Medical Sciences, 50(4), 1097 - 1105.en_US
dc.identifier.doi10.3906/sag-2002-179
dc.identifier.endpage1105en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue4en_US
dc.identifier.pmid32394684
dc.identifier.scopus2-s2.0-85088613901
dc.identifier.scopusqualityQ1
dc.identifier.startpage1097en_US
dc.identifier.trdizinid354748
dc.identifier.urihttps://doi.org/10.3906/sag-2002-179
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpVME56UTRPQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12587/13356
dc.identifier.volume50en_US
dc.identifier.wosWOS:000549845300002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleComparison of the efficacy between bilateral proximal tubal occlusion and total salpingectomy on ovarian reserve and the cholinergic system: an experimental studyen_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
sag-50-4-58-2002-179.pdf
Boyut:
1.66 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WOS İndeksli Yayınlar Koleksiyonu