Evaluation of serum resistin levels in patients with ocular and non-ocular Behcet's disease

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dc.contributor.authorYalcindag, F. Niluefer
dc.contributor.authorYalcindag, Ali
dc.contributor.authorBatioglu, Figen
dc.contributor.authorCaglayan, Osman
dc.contributor.authorKisa, Ucler
dc.contributor.authorOzdemir, Ozden
dc.date.accessioned2020-06-25T17:44:25Z
dc.date.available2020-06-25T17:44:25Z
dc.date.issued2008
dc.departmentKırıkkale Üniversitesi
dc.descriptionBatioglu, Figen/0000-0002-5834-7512; KISA, Ucler/0000-0002-8131-6810
dc.description.abstractBackground: Resistin, a recently identified adipocytokine, has been found to play an important role in inflammation and the processes of inflammation-related diseases. Serum resistin levels in patients with Behcet's disease (BD) have not yet been investigated. We aimed to evaluate the relation between resistin and interleukin-6 (IL-6) in Behcet patients with or without ocular involvement and in normal controls. Methods: Twenty-two patients with BID and 19 healthy control subjects were included in this study. While 14 patients had posterior segment involvement of the eye, the other 8 did not have ocular disease. Serum resistin and interleukin-6 (IL-6), levels were measured in all samples. Data from all groups were tested for statistical significance. Results: The mean resistin and IL-6 concentrations were significantly higher in patients with BD than the control subjects (p = 0.011 and p = 0.0001, respectively). There was a significant difference in resistin and IL-6 levels between the patients with non-ocular BID and controls (p = 0.013 and p = 0.0001, respectively), as well as resistin and IL-6 levels between the ocular BD group and the control group (p = 0.05 and p = 0.0001, respectively). However, there was no significant difference between patients with ocular versus non-ocular BID.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.3129/i08-081
dc.identifier.endpage475en_US
dc.identifier.issn0008-4182
dc.identifier.issue4en_US
dc.identifier.pmid18711464
dc.identifier.scopus2-s2.0-49949089310
dc.identifier.scopusqualityQ2
dc.identifier.startpage473en_US
dc.identifier.urihttps://doi.org/10.3129/i08-081
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4105
dc.identifier.volume43en_US
dc.identifier.wosWOS:000258854000015
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCanadian Ophthal Socen_US
dc.relation.ispartofCanadian Journal Of Ophthalmology-Journal Canadien D Ophtalmologie
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBehcet's diseaseen_US
dc.subjectresistinen_US
dc.subjectinterleukin-6en_US
dc.subjectocular involvementen_US
dc.titleEvaluation of serum resistin levels in patients with ocular and non-ocular Behcet's diseaseen_US
dc.typeArticle

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