Prognostic value of oxygen saturation and heart rate during a six-minute walk test in pediatric pulmonary hypertension

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dc.authoridÇelik, Bülent/0000-0002-0481-4808
dc.authoridKula, Serdar/0000-0002-0728-1648
dc.contributor.authorAtasayan, Vildan
dc.contributor.authorCanbeyli, Fatma
dc.contributor.authorTunaoglu, Fatma Sedef
dc.contributor.authorOğuz, Ayşe Deniz
dc.contributor.authorÇelik, Bülent
dc.contributor.authorKula, Serdar
dc.date.accessioned2025-01-21T16:34:26Z
dc.date.available2025-01-21T16:34:26Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground/aim: Th evaluate the pre and post-treatment heart rate and oxygen (O-2) saturation values measured before, during and after 6MWT in children who received PAH-specific treatment and to determine the effect of these variables on prognosis. Materials and methods: This retrospective study included 29 patients who were diagnosed as PAH and treated. The transcutaneous O-2 saturation and heart rate levels were recorded before the test: baseline (Sat0, HR0), at the end of the test: exercise (Sal1, HR1) and 5 min after the test: recovery (Sat2, HR2). The increase in heart rate was defined as HR1-HR0 and the decrease in saturation as Sat0-Sat1. The results obtained before and after the PAH-specific treatment were analyzed and their effect on survival was assessed. Results: Fifteen of 29 patients were female (51.7%). The mean age was 127.2 +/- 44.8 months and the median follow-up time was 60 (12-156) months. Only pre-treatment HR1 was found associated with survival. The mean HR1 value of survivors was 122.8 +/- 18.4 and that of deceased 94.3 +/- 19.1 (p = 0.03). Post-treatment 6MWT was associated with survival. It was 453.3 +/- 96.5 in for survivors and 250 +/- 135.2 m for deceased (p = 0.02). Conclusion: Post-treatment 6MWT, FC and proBNP had prognostic value in pediatric patients with PAH. The decrease in saturation and increase in heart rate were not found to have a prognostic value. Pre-treatment HR1 was associated with survival. Identification of these prognostic factors at the beginning and throughout the treatment may be a guide for detecting the severity of the disease and follow-up.
dc.identifier.doi10.3906/sag-2004-220
dc.identifier.endpage1840
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue4
dc.identifier.pmid33754651
dc.identifier.scopus2-s2.0-85114231112
dc.identifier.scopusqualityQ1
dc.identifier.startpage1833
dc.identifier.trdizinid480476
dc.identifier.urihttps://doi.org/10.3906/sag-2004-220
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay480476
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23967
dc.identifier.volume51
dc.identifier.wosWOS:000691544700031
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTubitak Scientific & Technological Research Council Turkey
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subject6-minute walk test; pulmonary arterial hypertension; survival; heart rate
dc.titlePrognostic value of oxygen saturation and heart rate during a six-minute walk test in pediatric pulmonary hypertension
dc.typeArticle

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