Incidence of iodine deficiency in Turkish patients with congenital hypothyroidism

Basit Öğe Kaydı
dc.contributor.authorEvliyaoglu, Olcay
dc.contributor.authorKutlu, Alev
dc.contributor.authorKara, Cengiz
dc.contributor.authorAtavci, Sevil G.
dc.date.accessioned2020-06-25T17:44:37Z
dc.date.available2020-06-25T17:44:37Z
dc.date.issued2008
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: Turkey is located in an area of mild to moderate iodine deficiency. The aim of the present study was to investigate the incidence of iodine deficiency in patients with congenital hypothyroidism. Methods: Twenty five patients with a median age of 12 days (6 days-6 months) at diagnosis and followed for a median time of 7 months (1-60 months) were enrolled in the study. Thyroid function tests, thyroid scintigraphy, ultrasonography and urine iodine measurements of the patients and mothers were performed. Results and conclusion: Congenital hypothyroidism was diagnosed within postnatal day 13, between days 13 and 30, and after 30 days of age in 68%, 20% and 12% of the patients, respectively. At the time of diagnosis mean serum thyroid-stimulating hormone and total T4 were 85.3 +/- 27.6 mIU/L and 3.9 +/- 2.8 mu g/dL, respectively. Incidence of iodine deficiency was 36% in the patients (median, 110 mu g/L) and 88% in the mothers (median, 40 mu g/L). Thyroid scintigraphy and ultrasound were normal in all of the patients with iodine deficiency. At scintigraphic evaluation, thyroid gland was not visualized in 28% of patients; in the patients whose thyroid glands were not visualized scintigraphic ally thyroid ultrasonography indicated agenesis in 57%, and hypoplasia in 43%. In all the patients with thyroid agenesis or hypoplasia iodine levels were normal. In 36% of the patients imaging studies of thyroid gland and urine iodine measurements were normal. Despite salt iodization program, incidence of iodine deficiency is still high in patients with congenital hypothyroidism and mothers. National measures are urgently required for correction of iodine deficiency in Turkey.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1111/j.1442-200X.2008.02569.x
dc.identifier.endpage280en_US
dc.identifier.issn1328-8067
dc.identifier.issue3en_US
dc.identifier.pmid18533935
dc.identifier.scopus2-s2.0-44649090712
dc.identifier.scopusqualityQ3
dc.identifier.startpage276en_US
dc.identifier.urihttps://doi.org/10.1111/j.1442-200X.2008.02569.x
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4153
dc.identifier.volume50en_US
dc.identifier.wosWOS:000257668200002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBlackwell Publishingen_US
dc.relation.ispartofPediatrics International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcongenitalen_US
dc.subjecthypothyrodismen_US
dc.subjectiodineen_US
dc.titleIncidence of iodine deficiency in Turkish patients with congenital hypothyroidismen_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Incidence of iodine deficiency in Turkish patients with congenital hypothyroidism.pdf
Boyut:
89.58 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu