Local anesthesia in transrectal ultrasound-guided prostate biopsy: EMLA cream as a new alternative technique

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dc.contributor.authorBasar, Hülya
dc.contributor.authorBasar, M. Murad
dc.contributor.authorÖzcan, Şaziye
dc.contributor.authorAkpinar, Serpil
dc.contributor.authorBasar, Halil
dc.contributor.authorBatislam, Ertan
dc.date.accessioned2020-06-25T17:40:42Z
dc.date.available2020-06-25T17:40:42Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description7th Seminar of the International-Cooperative-Study-of-Diagnostic-Ultrasound-and-Prostate-Cancer -- JUN 03-04, 2004 -- Tokyo, JAPAN
dc.descriptionBatislam, Ertan/0000-0002-7493-4573
dc.description.abstractObjectives. The aims of the present study were to evaluate the efficacy of eutectic mixture of local anesthetics ( EMLA) cream in transrectal-guided prostate biopsy and to compare its effect with that of other injectable anesthetic procedures. Material and methods. Eighty male patients with prostate-specific antigen (PSA) levels >4 ng/ml or who had prostate nodules on digital rectal examination were randomly divided into four groups. In Group 1 ( controls), prostate biopsy was performed after application of a placebo cream. In Group 2, local surface anesthesia with EMLA cream was performed 15 min before biopsy. Periprosthetic nerve blockade was performed with 1% prilocaine and 1% lidocaine in Groups 3 and 4, respectively. Pain was evaluated using a visual analog scale (VAS) after each core biopsy. In addition, blood pressure, heart rate and oxygen saturations were recorded after each biopsy and then at 5-min intervals for 15 min. Results. Average VAS scores in Groups 1-4 were 5.5, 2.9, 2.4 and 2.2, respectively. There was a statistically significant difference in VAS scores between the treatment groups and the placebo group (p=0.000). There were no statistically significant differences in VAS scores between the three treatment groups (p(2-3) = 0.126, p(2-4) = 0.303, p(3-4) = 0.537). We detected no statistically significant differences between the groups based on the hemodynamic data (p(MAP) = 0.899). Moreover, these measurements did not show statistically significant changes with time in any of the groups (p > 0. 05). Conclusion. Intrarectal application of EMLA cream provides equal anesthesia to periprostatic nerve blockade with prilocaine and lidocaine.en_US
dc.description.sponsorshipInt Cooperat Study Diagnost Ultrasound & Prostate Cancen_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1080/00365590510007810
dc.identifier.endpage134en_US
dc.identifier.issn0036-5599
dc.identifier.issue2en_US
dc.identifier.pmid16019766
dc.identifier.scopus2-s2.0-18244375015
dc.identifier.scopusqualityN/A
dc.identifier.startpage130en_US
dc.identifier.urihttps://doi.org/10.1080/00365590510007810
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3529
dc.identifier.volume39en_US
dc.identifier.wosWOS:000228326200005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherInforma Healthcareen_US
dc.relation.ispartofScandinavian Journal Of Urology And Nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecteutectic mixture of local anesthetics creamen_US
dc.subjectlidocaineen_US
dc.subjectlocal anesthesiaen_US
dc.subjectprilocaineen_US
dc.subjectprostate biopsyen_US
dc.titleLocal anesthesia in transrectal ultrasound-guided prostate biopsy: EMLA cream as a new alternative techniqueen_US
dc.typeArticle

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