The effect of aging on the apparent diffusion coefficient of normal appearing white and gray matter

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dc.contributor.authorKaradeniz Bilgili Y.M.
dc.contributor.authorUnal B.
dc.contributor.authorKendi T.
dc.contributor.authorSimşir I.
dc.contributor.authorErdal H.
dc.contributor.authorHuvaj S.
dc.contributor.authorKara S.
dc.date.accessioned2020-06-25T15:13:25Z
dc.date.available2020-06-25T15:13:25Z
dc.date.issued2004
dc.departmentKırıkkale Üniversitesi
dc.description.abstractPURPOSE: To test if the apparent diffusion coefficient (ADC) values reflect the ultrastructural changes of normal appearing white and gray matter with advancing age. MATERIALS AND METHODS: We selected 45 patients with normal MRI and DW imaging findings. DW and MRI imaging was performed and for each patient the average ADC on trace images of the frontal and occipital white matter and the thalamus were compared with increasing patient age. RESULTS: The average ADC value was 0.753+/-0.054 x 10-3 mm2/sec in frontal white matter, 0.673+/-0.085 x 10-3 mm2/sec in occipital white matter, and 0.763+/-0.063 x 10-3 mm2/sec in the thalamus. For white matter, ADC values increased with advancing age. Although ADC tended to increase with age, comparison of individual thalamic ADC and patient ages did not reach statistical significance. CONCLUSION: Advancing age is associated with a small but statistically significant increase of water diffusibility in human white matter. This increase may reflect mild structural changes with normal aging.en_US
dc.identifier.citationBu makale açık erişimli değildir.en_US
dc.identifier.endpage7en_US
dc.identifier.issn13004360
dc.identifier.issue1en_US
dc.identifier.pmid15054694
dc.identifier.scopus2-s2.0-2942748376
dc.identifier.scopusqualityN/A
dc.identifier.startpage4en_US
dc.identifier.trdizinidtrdizinikyoktur
dc.identifier.urihttps://hdl.handle.net/20.500.12587/1788
dc.identifier.volume10en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isotr
dc.relation.ispartofTanisal ve girişimsel radyoloji : Tibbi Görüntüleme ve Girişimsel Radyoloji Dernegi yayin organi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleThe effect of aging on the apparent diffusion coefficient of normal appearing white and gray matteren_US
dc.title.alternativeMRG ile normal görünümlü beyaz ve gri cevherde yaşlanmanin etkilerinin ADC degerleri ile saptanabilirligi.en_US
dc.typeArticle

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