Effect of intravitreal bevacizumab on retrobulbar blood flow of patients with diabetic macular edema

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dc.contributor.authorÖrnek, Nurgül
dc.contributor.authorİnal, Mikail
dc.contributor.authorErbahceci, Inci Elif
dc.contributor.authorOğurel, Tevfik
dc.contributor.authorÖrnek, Kemal
dc.date.accessioned2020-06-25T18:12:41Z
dc.date.available2020-06-25T18:12:41Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.descriptionOrnek, Nurgul/0000-0003-3068-1831; INAL, MIKAIL/0000-0003-0642-7913;
dc.description.abstractPurpose: To determine the effect of intravitreal bevacizumab on retrobulbar blood flow of patients with diabetic macular edema. Methods: Peak systolic velocity, end-diastolic velocity, resistance, and pulsatility indices of central retinal artery (CRA), nasal posterior ciliary artery (NPCA), temporal posterior ciliary artery (TPCA), and ophthalmic artery (OA) were assessed by color Doppler ultrasonography in injected and uninjected eyes of 37 patients at baseline and at day 1 and day 7 after the injection. Results: At day 1 after the injection, peak systolic and end diastolic velocities of the CRA and NPCA in the injected eyes and peak systolic velocity of NPCA in the uninjected eyes decreased significantly (p<0.05, p = 0.025, respectively). Peak systolic and end diastolic velocities were not significantly different in the injected and uninjected eyes at day 7 after the injection (p>0.05). In the injected eyes, there was no significant change in resistance and pulsatility indices (p>0.05), but a decrease in resistance index of NPCA and resistance and pulsatility indices of TPCA occurred in uninjected eyes at day 7 after the injection (p = 0.016, p = 0.023, and p = 0.025, respectively). Conclusions: Intravitreal bevacizumab affects retrobulbar blood flow in injected and uninjected eyes of patients with diabetic macular edema.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.5301/ejo.5000617
dc.identifier.endpage545en_US
dc.identifier.issn1120-6721
dc.identifier.issn1724-6016
dc.identifier.issue6en_US
dc.identifier.pmid25907286
dc.identifier.scopus2-s2.0-84945975880
dc.identifier.scopusqualityQ2
dc.identifier.startpage539en_US
dc.identifier.urihttps://doi.org/10.5301/ejo.5000617
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6010
dc.identifier.volume25en_US
dc.identifier.wosWOS:000366484400023
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWichtig Publen_US
dc.relation.ispartofEuropean Journal Of Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBevacizumaben_US
dc.subjectColor doppler ultrasonographyen_US
dc.subjectDiabetic macular edemaen_US
dc.subjectRetrobulbar blood flowen_US
dc.titleEffect of intravitreal bevacizumab on retrobulbar blood flow of patients with diabetic macular edemaen_US
dc.typeArticle

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