Genotoxicity testing of some organophosphate insecticides in the Drosophila wing spot test

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dc.contributor.authorÇakır, Şükran
dc.contributor.authorSarıkaya, Rabia
dc.date.accessioned2020-06-25T17:40:44Z
dc.date.available2020-06-25T17:40:44Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description.abstractIn this study, different concentrations of some organophosphate insecticides (methyl parathion, azamethiphos, dichlorvos and diazinon) have been evaluated for genotoxicity in the wing somatic mutation and recombination test (SMART) of Drosophila melanogaster. Third-instar larvae trans-heterozygous for two genetic markers mwh and flr, were treated at different concentrations (1 ppm, 3 ppm, 5 ppm, 7 ppm, 10 ppm) of the test compounds. A positive correlation was observed between total mutations and the number of wings having mutations. In addition, the observed mutations were classified according to size and type of mutation per wing. Chemicals used were ranked in decreasing order according to their genotoxic effects as diazinon, dichlorvos, methyl parathion, azamethiphos. (C) 2004 Elsevier Ltd. All rights reserved.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.fct.2004.11.010
dc.identifier.endpage450en_US
dc.identifier.issn0278-6915
dc.identifier.issn1873-6351
dc.identifier.issue3en_US
dc.identifier.pmid15680680
dc.identifier.scopus2-s2.0-12844255015
dc.identifier.scopusqualityQ1
dc.identifier.startpage443en_US
dc.identifier.urihttps://doi.org/10.1016/j.fct.2004.11.010
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3536
dc.identifier.volume43en_US
dc.identifier.wosWOS:000226962400007
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofFood And Chemical Toxicology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDrosophila melanogasteren_US
dc.subjectsomatic mutation and recombination testen_US
dc.subjectorganophosphate insecticidesen_US
dc.subjectgenetic toxicologyen_US
dc.titleGenotoxicity testing of some organophosphate insecticides in the Drosophila wing spot testen_US
dc.typeArticle

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