Atraumatic Osteonecrosis After Estrogen Replacement Therapy Associated with Low Protein S Level in a Patient with Turner Syndrome

Özet

Atraumatic osteonecrosis has been associated with a variety of clinical conditions including corticosteroid usage, alcoholism, infections, hyperbaric events, storage disorders, marrow-infiltrating diseases, coagulation defects, and some autoimmune diseases. Osteonecrosis due to thrombophilia is an extremely rare condition with only few cases reported previously in the literature. Hormone-replacement therapies cause increased risk of venous thrombosis, probably by causing a synergistic effect with inherited clotting defects. In this article, we report a young female with Turner syndrome, who developed avascular necrosis of the femoral head during treatment with oral estrogen, which was associated with low protein S levels.

Açıklama

Haznedaroglu, Ibrahim C./0000-0001-8028-9462; Haznedaroglu, Ibrahim C./0000-0001-8028-9462

Anahtar Kelimeler

osteonecrosis, protein S deficiency, estrogen

Kaynak

Clinical And Applied Thrombosis-Hemostasis

WoS Q Değeri

Q3

Scopus Q Değeri

Q2

Cilt

16

Sayı

5

Künye

Ureten, K., Ozturk, M. A., Bostanci, A., Ceneli, O., Ozbek, M., & Haznedaroglu, I. C. (2010). Atraumatic osteonecrosis after estrogen replacement therapy associated with low protein S level in a patient with Turner syndrome. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 16(5), 599–601. https://doi.org/10.1177/1076029609339746