Immunohistochemical investigation of the damage to and repair of myelin, and astrocyte activity in small ruminants resulting from with natural meningoencephalitic listeriosis

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dc.contributor.authorOzyildiz, Zafer
dc.contributor.authorDincel, Gungor Cagdas
dc.contributor.authorTerzi, Osman Safa
dc.contributor.authorOzsoy, Sule Yurdagul
dc.contributor.authorKul, Oguz
dc.date.accessioned2020-06-25T18:30:01Z
dc.date.available2020-06-25T18:30:01Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.descriptionDINCEL, Gungor Cagdas/0000-0002-6985-3197
dc.description.abstractMeningoencephalitic listeriosis is a significant bacterial disease in various species. Common characteristics include microabscesses in the brainstem, midbrain and cerebellum. Many aspects of damage to the central nervous system caused by the disease remain obscure. We investigated central nervous system damage by assessing the presence of biomarkers such as galactocerebroside (GAL-C), glial fibrilary acidic protein (GFAP) and myelin basic protein (MBP) in brain tissues of sheep and goats of various ages, which naturally infected with listeriosis. We examined sections of pons, medulla oblongata, rostral colliculus, cerebellum, thalamus and cornu ammonis and found increased MBP (P < 0.01), GAL-C (P < 0.01) and GFAP (P < 0.01) expression. Ihis studv showed that myelin damage in meningoencephalitic listeriosis was an important neuropathological finding. The most prominent finding of this study is the beginning of the regeneration as soon as myelin damage occurs.en_US
dc.identifier.citationÖzyıldız, Z. , Dinçel, G. Ç. , Terzi, O. S. , Özsoy, Ş. Y. & Kul, O. (2018). Immunohistochemical investigation of the damage to and repair of myelin, and astrocyte activity in small ruminants resulting from with natural meningoencephalitic listeriosis . Ankara Üniversitesi Veteriner Fakültesi Dergisi , 65 (3) , 283-290 .en_US
dc.identifier.doi10.1501/Vetfak_0000002858
dc.identifier.endpage290en_US
dc.identifier.issn1300-0861
dc.identifier.issn1308-2817
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85047499880
dc.identifier.scopusqualityQ3
dc.identifier.startpage283en_US
dc.identifier.trdizinid286062
dc.identifier.urihttps://doi.org/10.1501/Vetfak_0000002858
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7534
dc.identifier.volume65en_US
dc.identifier.wosWOS:000437083800009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherAnkara Univ Pressen_US
dc.relation.ispartofAnkara Universitesi Veteriner Fakultesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAstrocytesen_US
dc.subjectGAL-Cen_US
dc.subjectGFAPen_US
dc.subjectListeria monocytogenesen_US
dc.subjectMBPen_US
dc.titleImmunohistochemical investigation of the damage to and repair of myelin, and astrocyte activity in small ruminants resulting from with natural meningoencephalitic listeriosisen_US
dc.typeArticle

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