The utility of F-18-FDG PET/CT in solitary fibrous tumors of the pleura

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dc.contributor.authorTazeler, Z.
dc.contributor.authorTan, G.
dc.contributor.authorAslan, A.
dc.contributor.authorTan, S.
dc.date.accessioned2020-06-25T18:16:36Z
dc.date.available2020-06-25T18:16:36Z
dc.date.issued2016
dc.departmentKırıkkale Üniversitesi
dc.descriptionAslan, Ahmet/0000-0003-1433-6149
dc.description.abstractObjective: To demonstrate the utility of F-18-FDG PET/CT in the differentiation of benign and malignant solitary fibrous tumors of the pleura (SFTP). Materials and methods: A retrospective review was performed on the F-18-FDG PET/CT data from 17 patients with histopathologically diagnosed benign or malignant SFTP. The size, side of SFTP, presence of necrosis, calcification, pleural effusion, hilar lymphadenopathy (LAP), density on CT images (Hounsfield unit-HU), and F-18-FDG uptake (SUVmax) were recorded and compared in order to detect malignant SFTP. Statistical significance was set as p < 0.05. Results: The difference in size, presence of necrosis, and hilar LAP on CT images were statistically significant (p = 0.004, p < 0.001, p = 0.015, respectively) in a comparison of benign and malignant SFTPs. The mean HU of benign SFTP was 46.16 +/- 5.52 HU, and for malignant SFTP it was 35.03 +/- 4.61 HU (p = 0.003). The mean SUVmax was 3.02 +/- 1.02 for benign SFTP and 4.89 +/- 2.12 for malignant SFTP (p = 0.021). A cut-off value of >= 7 cm for size, <= 39.81 HU for density, and >= 3.47 for SUVmax was obtained by ROC analysis for detecting malignant SFTP. Conclusions: F-18-FDG PET/CT may have a limited role in diagnosing malignant SFTP in suspected patients. (C) 2015 Elsevier Espana, S.L.U. and SEMNIM. All rights reserved.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.remn.2015.10.003
dc.identifier.endpage170en_US
dc.identifier.issn2253-654X
dc.identifier.issue3en_US
dc.identifier.pmid26632105
dc.identifier.scopus2-s2.0-84961122811
dc.identifier.scopusqualityQ4
dc.identifier.startpage165en_US
dc.identifier.urihttps://doi.org/10.1016/j.remn.2015.10.003
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6574
dc.identifier.volume35en_US
dc.identifier.wosWOS:000375636000004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Doyma Slen_US
dc.relation.ispartofRevista Espanola De Medicina Nuclear E Imagen Molecular
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPleuraen_US
dc.subjectSolitary fibrous tumor of the pleuraen_US
dc.subjectF-18-FDG PET/CTen_US
dc.subjectF-18-FDG PETen_US
dc.subjectComputed tomographyen_US
dc.subjectMaximum standardized uptake valueen_US
dc.titleThe utility of F-18-FDG PET/CT in solitary fibrous tumors of the pleuraen_US
dc.typeArticle

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