Serum leptin levels in patients with ocular and nonocular Behcet's disease

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dc.contributor.authorYalçındağ, F. Nilufer
dc.contributor.authorKısa, Üçler
dc.contributor.authorBatioglu, Figen
dc.contributor.authorYalçındağ, Ali
dc.contributor.authorÖzdemir, Özden
dc.contributor.authorÇağlayan, Osman
dc.date.accessioned2020-06-25T17:44:07Z
dc.date.available2020-06-25T17:44:07Z
dc.date.issued2007
dc.descriptionBatioglu, Figen/0000-0002-5834-7512; KISA, Ucler/0000-0002-8131-6810
dc.description.abstractAims. To investigate serum leptin levels in Behcet's patients with or without ocular involvement compared with healthy subjects and the relationship between serum leptin and uveitis activity in patients with ocular involvement. Methods. Fifty-seven patients with Behcet's disease and 20 healthy control subjects were included in this study. While 27 patients had ocular involvement (18 had acute uveitis, 9 had inactive ocular involvement), 30 did not have ocular disease. C-reactive protein, alpha 1-antitrypsin, and serum leptin levels were measured in all samples. Results. There was a significant difference between the patients with Behchet's disease and control group for both logarithm of leptin (P = .000) and logarithm of CRP (P = .031). Logarithm of leptin in nonocular Behcet's patients was significantly higher compared to its level in ocular Behcet's disease and controls (P =.009). There was a significant difference between the patients with active ocular disease and control group (P = .03). Conclusions. Leptin might have a possible role in the pathogenesis of Behcet's disease. Copyright (c) 2007 F. Nilufer Yalciindag et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.identifier.citationYalçindağ, F. N., Kisa, U., Batioğlu, F., Yalçindağ, A., Ozdemir, O., & Cağlayan, O. (2007). Serum leptin levels in patients with ocular and nonocular Behçet's disease. Mediators of inflammation, 2007, 31986. https://doi.org/10.1155/2007/31986en_US
dc.identifier.doi10.1155/2007/31986
dc.identifier.issn0962-9351
dc.identifier.issn1466-1861
dc.identifier.pmid17641728
dc.identifier.scopus2-s2.0-34250891347
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org10.1155/2007/31986
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4014
dc.identifier.volume2007en_US
dc.identifier.wosWOS:000247595500001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHindawi Ltden_US
dc.relation.ispartofMediators Of Inflammation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleSerum leptin levels in patients with ocular and nonocular Behcet's diseaseen_US
dc.typeArticle

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