Seminal arginase activity in infertility
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Date
2000
Journal Title
Journal ISSN
Volume Title
Publisher
Springer Verlag
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
Arginase(Arg) activity in seminal plasma and sperm cells from infertile men and healthy fertile donors was measured. There were no statistically meaningful differences in seminal plasma Arg activity between the two groups whereas sperm cells from oligospermic infertile men had a higher Arg activity compared with the controls. Some important correlations were established between sperm count and Arg activity (negative values) and sperm motility and Arg activity (positive values) in both sperm cells and plasma samples from infertile men. Results suggest that the arginine-nitric oxide pathway within sperm cells from oligospermic infertile men is disturbed by enhanced Arg activity. We think that this may play a part in sperm dysfunction and male infertility.
Description
Elgun, Serenay/0000-0002-1751-090X
Keywords
arginase, seminal plasma, sperm cell, infertility
Journal or Series
Urological Research
WoS Q Value
Q3
Scopus Q Value
N/A
Volume
28
Issue
1
Citation
closedAccess
