CA 72-4 levels in patients with type 2 diabetes mellitus

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dc.contributor.authorDemirci, H.
dc.contributor.authorErdamar, H.
dc.contributor.authorKarakoc, A.
dc.contributor.authorAkturk, M.
dc.contributor.authorYilmaz, M.
dc.contributor.authorArslan, M.
dc.date.accessioned2020-06-25T17:51:23Z
dc.date.available2020-06-25T17:51:23Z
dc.date.issued2010
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: CA 72-4 is one of the blood group carbohydrate antigens which can be used as a tumour marker in ovarian, pancreatic and gastrointestinal carcinomas. It can also be elevated in various benign conditions including pancreatitis. Diabetes mellitus is a chronic disorder related with the pancreas. In this study, we investigated CA 72-4 levels in patients with type 2 diabetes and its relation to the metabolic status. Methods: Sixty-nine patients with type 2 diabetes mellitus (female/male = 40/29) and 60 healthy subjects (female/male = 35/25) participated in this study. The levels of serum CA 72-4 were measured and faecal occult blood tests (following 3 days of white diet were obtained for three consecutive days) were performed in all patients. Patients had a pathological finding for any of these two parameters were further investigated with upper gastrointestinal endoscopy, colonoscopy and computerised tomography. Results: The mean levels of CA 72-4 was 1.89 +/- 2.61 U/ml in the study group and 1.4 +/- 0.98 U/ml in the control group (p > 0.05). There was no association between CA 72-4 levels and age and sex of the patients, duration of diabetes, body mass index, biochemical indicators of metabolic control (the levels of HbA(1c), fasting and postprandial glucose, serum lipids), the presence of microvascular complications (retinopathy, nephropathy, neuropathy) or treatment modalities. Conclusions: Elevated levels of CA 72-4 in diabetic patients are not related to diabetes and it should be interpreted as evaluated in a non-diabetic patient.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1111/j.1742-1241.2007.01614.x
dc.identifier.endpage38en_US
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue1en_US
dc.identifier.pmid18205795
dc.identifier.scopus2-s2.0-72449146832
dc.identifier.scopusqualityQ1
dc.identifier.startpage34en_US
dc.identifier.urihttps://doi.org/10.1111/j.1742-1241.2007.01614.x
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4840
dc.identifier.volume64en_US
dc.identifier.wosWOS:000272655800007
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal Of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleCA 72-4 levels in patients with type 2 diabetes mellitusen_US
dc.typeArticle

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