Usefulness of CA 15-3 for breast or ovarian primary sites in metastatic adenocarcinoma of pleural fluid

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dc.contributor.authorOguztuzun, Serpil
dc.contributor.authorKilic, Murat
dc.contributor.authorTandogan, Nisa
dc.contributor.authorOzturk, Latif
dc.date.accessioned2020-06-25T18:06:51Z
dc.date.available2020-06-25T18:06:51Z
dc.date.issued2012
dc.departmentKırıkkale Üniversitesi
dc.descriptionKilic, Murat/0000-0002-1377-2021
dc.description.abstractThis study was conducted to evaluate the diagnostic value of CA 15-3, mammaglobin, c-erbB-2, estrogen receptor (ER), progesterone receptor (PR), CK 20, and CA 125 for detecting metastatic breast and ovarian carcinoma in pleural fluids. The material under study consisted of 26 pleural effusions from invasive breast and ovarian cancer patients from the Hannover Cytopathology Institute. Expressions of these markers were studied using immunocytochemistry. All of the breast cancer cases studied showed a positive reaction with CA 15-3, while only 36% with mammaglobin, 21% with c-erbB-2, 36% with ER, and 7% with PR were positive. The sensitivities of CK 20, CA 15-3, and CA 125 as markers for metastatic ovarian carcinoma were 43%, 88%, and 55%, respectively. Our results indicate that CA 15-3 has a higher sensitivity than other tumor markers for diagnosing metastatic breast and ovarian carcinoma in pleural fluids.en_US
dc.identifier.citationOğuztüzün S., Kılıç M., Tandoğan N., Öztürk L. (2012). Usefulness of CA 15-3 for breast or ovarian primary sites in metastatic adenocarcinoma of pleural fluid. Turkish Journal of Biology, 36(2), 171 - 175.en_US
dc.identifier.doi10.3906/biy-1003-76
dc.identifier.endpage175en_US
dc.identifier.issn1300-0152
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84857494847
dc.identifier.scopusqualityQ1
dc.identifier.startpage171en_US
dc.identifier.trdizinid127767
dc.identifier.urihttps://doi.org/10.3906/biy-1003-76
dc.identifier.urihttps://hdl.handle.net/20.500.12587/5380
dc.identifier.volume36en_US
dc.identifier.wosWOS:000302197000005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPleuraen_US
dc.subjectmetastasisen_US
dc.subjectbreast canceren_US
dc.subjectovarian canceren_US
dc.subjectCA 15-3en_US
dc.subjectcytologyen_US
dc.titleUsefulness of CA 15-3 for breast or ovarian primary sites in metastatic adenocarcinoma of pleural fluiden_US
dc.typeArticle

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