Probiotics, Live Biotherapeutic Products (LBPs), and Gut-Brain Axis Related Psychological Conditions: Implications for Research and Dietetics

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dc.authoridÖzoğul, Fatih/0000-0002-0655-0105
dc.authoridBingöl, Feray Gencer/0000-0001-5754-7208
dc.contributor.authorAğagündüz, Duygu
dc.contributor.authorÇelik, Elif
dc.contributor.authorCemali, Özge
dc.contributor.authorBingöl, Feray Gencer
dc.contributor.authorÖzenir, Çiler
dc.contributor.authorÖzoğul, Fatih
dc.contributor.authorCapasso, Raffaele
dc.date.accessioned2025-01-21T16:43:46Z
dc.date.available2025-01-21T16:43:46Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractIt is well-known that probiotics have key roles in the crosstalk between the gut and brain in terms of nutrition and health. However, when investigating their role in nutrition and health, it can be important to discriminate probiotics used as foods, food supplements, or drugs. For clarification of this terminology, the Food and Drug Administration (FDA) has established a new live biotherapeutic products (LBP) category, expressing pharmaceutical expectations and to reduce confusion in the literature. Growing evidence advises that the community of microorganisms found in the gut microbiota is associated with psychological conditions. Hence, it is thought that LBPs may positively affect depression, anxiety, bipolar disorder, and schizophrenia by reducing inflammation, improving gut microbiota, and balancing gut neurometabolites. This review focuses on the specific position of probiotics as LBPs in psychological conditions. Condition-specific potential pathways and mechanisms of LBPs and the prominent strains are discussed in the light of novel studies for future research, dietetic and pharmaceutical applications.
dc.identifier.doi10.1007/s12602-023-10092-4
dc.identifier.endpage1031
dc.identifier.issn1867-1306
dc.identifier.issn1867-1314
dc.identifier.issue4
dc.identifier.pmid37222849
dc.identifier.scopus2-s2.0-85160261384
dc.identifier.scopusqualityQ1
dc.identifier.startpage1014
dc.identifier.urihttps://doi.org/10.1007/s12602-023-10092-4
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25319
dc.identifier.volume15
dc.identifier.wosWOS:000994090700001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofProbiotics and Antimicrobial Proteins
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectLive biotherapeutic products (LBPs); Gut-brain axis; Probiotics; Psychological conditions
dc.titleProbiotics, Live Biotherapeutic Products (LBPs), and Gut-Brain Axis Related Psychological Conditions: Implications for Research and Dietetics
dc.typeArticle

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