Leptin resistance and genetic predisposition as potential mechanisms in the development of skin tags

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dc.contributor.authorErkek, E.
dc.contributor.authorKisa, U.
dc.contributor.authorBagci, Y.
dc.contributor.authorSezikli, H.
dc.date.accessioned2020-06-25T17:51:41Z
dc.date.available2020-06-25T17:51:41Z
dc.date.issued2011
dc.departmentKırıkkale Üniversitesi
dc.descriptionKISA, Ucler/0000-0002-8131-6810
dc.description.abstractBackground and objective: The cause of skin tags (ST) remains elusive. The present study was designed to elucidate the role of leptin and to unravel other potential aetiological factors in the pathogenesis of ST. Methods: The study population comprised 58 patients with ST and 24 control individuals. Demographic and other variables were recorded. A detailed laboratory evaluation including serum leptin was performed. Results: Statistical analysis revealed significant differences between the two groups in terms of body weight, body mass index (BMI), family history of ST, triglyceride, cholesterol, low-density lipoprotein (LDL), very low-density lipoprotein (VLDL) and serum leptin levels. A family history of ST was the most important predictor of ST development by logistic regression analysis. Conclusions: These findings indicate that ST correlate with serum leptin levels and that leptin resistance may be involved in the pathogenesis of ST in susceptible individuals.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage114en_US
dc.identifier.issn1814-7453
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-80053197500
dc.identifier.scopusqualityQ4
dc.identifier.startpage108en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/4953
dc.identifier.volume19en_US
dc.identifier.wosWOS:000295428500002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherMedcom Ltden_US
dc.relation.ispartofHong Kong Journal Of Dermatology & Venereology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcrochordonen_US
dc.subjectdiabetesen_US
dc.subjectinsulinen_US
dc.subjectleptinen_US
dc.subjectobesityen_US
dc.subjectskin tagen_US
dc.subjectsoft fibromaen_US
dc.titleLeptin resistance and genetic predisposition as potential mechanisms in the development of skin tagsen_US
dc.typeArticle

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