Restless legs syndrome in a bipolar disorder patient treated with olanzapine: is there an association?

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dc.contributor.authorButurak, Sadiye Visal
dc.contributor.authorTiryaki, Duygu
dc.contributor.authorDag, Ersel
dc.contributor.authorTurkel, Yakup
dc.date.accessioned2020-06-25T18:13:04Z
dc.date.available2020-06-25T18:13:04Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe aim of this case report is to report a case of restless legs syndrome (RLS) in a patient with bipolar disorder (BD) caused by olanzapine and to draw attention to possible relationship between BD and RLS. A female patient was diagnosed with mixed episode of BD. Olanzapine 10 mg/day was added to the extended release valproic acid 1000 mg/d treatment that the patient was using. In the next day after the beginning of olanzapine, itching, aching and tingling sensations begun in her legs at rest. She was diagnosed as RLS caused by olanzapine. Then the dose of olanzapine gradually reduced. But the symptoms were continuing at the dose of 2.5 mg/day. RLS symptoms disappeared in the next day after discontinuation of olanzapine. RLS has comorbidity with some psychiatric and neurologic disorders such as attention deficit/hyperactivity disorder (ADHD), depressive disorders, migraine. There are studies that showed genetic relationship between BD and both migraine and ADHD. As a result there might be an association between BD and RLS. These may account for the appearance of RLS with low dose olanzapine in this case. To our knowledge there are no studies about the association between BD and RLS and further research are needed on this subject.en_US
dc.identifier.citationButurak Ş. V., Tiryaki D.,Dağ E., Türkel Y. (2015). Restless legs syndrome in a bipolar disorder patient treated with olanzapine: is there an association?. Anadolu Psikiyatri Dergisi, 16(4), 301 - 303.en_US
dc.identifier.doi10.5455/apd.155781
dc.identifier.endpage303en_US
dc.identifier.issn1302-6631
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84923004429
dc.identifier.scopusqualityQ3
dc.identifier.startpage301en_US
dc.identifier.trdizinid175074
dc.identifier.urihttps://doi.org/10.5455/apd.155781
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6118
dc.identifier.volume16en_US
dc.identifier.wosWOS:000349324400011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherCumhuriyet Univ Tip Fak Psikiyatri Anabilim Dalien_US
dc.relation.ispartofAnadolu Psikiyatri Dergisi-Anatolian Journal Of Psychiatry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectrestless legs syndromeen_US
dc.subjectbipolar disorderen_US
dc.subjectassociationen_US
dc.subjectolanzapineen_US
dc.titleRestless legs syndrome in a bipolar disorder patient treated with olanzapine: is there an association?en_US
dc.typeArticle

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