Cerebral haemodynamics in patients with pseudoexfoliation glaucoma

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dc.contributor.authorAkarsu, Cengiz
dc.contributor.authorÜnal, Birsen
dc.date.accessioned2020-06-25T17:40:17Z
dc.date.available2020-06-25T17:40:17Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description24th National Radiology Congress -- OCT 08-11, 2003 -- Ankara, TURKEY
dc.description.abstractPurpose To evaluate the cerebral haemodynamics in patients with pseudoexfoliation glaucoma. Methods A total of 19 consecutive patients with pseudoexfoliation glaucoma and 19 age- and sex- matched healthy volunteers were recruited in a prospective comparative study. The affected eye in patients with unilateral glaucoma and the eye with more advanced lesions in patients with bilateral glaucoma were included in the study, and the ipsilateral middle cerebral arteries (MCA) were evaluated. While in the controls, the study eye and the ipsilateral MCA were chosen randomly. Measurements included systemic arterial pressure, heart rate, intraocular pressure (IOP), and transcranial colour Doppler parameters, including peak systolic velocity (PSV), end-diastolic velocity (EDV), time-averaged maximum velocity (TAMAX), resistivity index (RI), and pulsatility index (PI). Results The mean PSV, EDV, and TAMAX were significantly lower in the patients with pseudoexfoliation glaucoma than in healthy controls (P < 0.001, < 0.001 and < 0.001, respectively). Additionally, patients with pseudoexfoliation glaucoma had significantly higher PI and RI than healthy controls (P = 0.001 and 0.04, respectively). Systolic and iastolic blood pressures (P = 0.19 and 0.91, respectively) and heart rate (P = 0.06) were not different between the groups. The mean IOP were significantly higher in the glaucoma patients compared with the controls (P < 0.001). Conclusion This study suggests that pseudoexfoliation glaucoma is associated with a reduction in the blood flow velocity and elevation in the resistance of the MCA.en_US
dc.identifier.citationAkarsu, C., Űnal, B. (2005). Cerebral haemodynamics in patients with pseudoexfoliation glaucoma. Eye 19(12), 1297–1300 https://doi.org/10.1038/sj.eye.6701776en_US
dc.identifier.doi10.1038/sj.eye.6701776
dc.identifier.endpage1300en_US
dc.identifier.issn0950-222X
dc.identifier.issue12en_US
dc.identifier.pmid15650760
dc.identifier.scopus2-s2.0-31444432057
dc.identifier.scopusqualityQ1
dc.identifier.startpage1297en_US
dc.identifier.urihttps://doi.org/10.1038/sj.eye.6701776
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3375
dc.identifier.volume19en_US
dc.identifier.wosWOS:000233857300010
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherNature Publishing Groupen_US
dc.relation.ispartofEye
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectpseudoexfoliation glaucomaen_US
dc.subjectcerebral haemodynamicsen_US
dc.subjecttranscranial colour Doppleren_US
dc.titleCerebral haemodynamics in patients with pseudoexfoliation glaucomaen_US
dc.typeArticle

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