Is there a relationship between Parkinsons disease and Chlamydia pneumoniae

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dc.contributor.authorTurkel, Y.
dc.contributor.authorDag, E.
dc.contributor.authorGunes, H. N.
dc.contributor.authorApan, T.
dc.contributor.authorYoldas, T. K.
dc.date.accessioned2020-06-25T18:13:01Z
dc.date.available2020-06-25T18:13:01Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjectives: The aim was to investigate a possible relationship between Chlamydia pneumoniae and Parkinsons disease (PD). Study Design: Serum samples obtained from a cohort of 51 patients with PD and from 37 age- and sex-matched controls were assessed for the presence of antibodies. The control group was selected from healthy people. In both groups, 5 mL of blood was taken and after centrifugation frozen at -80 degrees C. Presence and concentration for C. pneumoniae IgM and IgG were determined by the enzyme linked immunosorbent assay (ELISA) and immunofluorescence (IFA), using C. pneumoniae IgG and IgM kit (Euroimmun, Germany). Results: Chlamydia pneumoniae IgG was positive in 50 (98%) patients in ELISA study. C. pneumoniae IgG was positive in 34 (92%) control subjects in ELISA study. C. pneumoniae IgG positivity in patients was slightly higher, but the difference did not reach statistical significance (P = 0.17). No statistically significant difference was found between the patient and the control groups in IFA study (P >= 0.5). C. pneumoniae IgM results (both ELISA and IFA study) was negative in the both PD group and control group.en_US
dc.description.sponsorshipKirikkale University Scientific Research Projects UnitKirikkale Universityen_US
dc.description.sponsorshipThe Kirikkale University Scientific Research Projects Unit, Conflict of Interest: None declared.en_US
dc.identifier.citationTurkel, Y., Dag, E., Gunes, H. N., Apan, T., & Yoldas, T. K. (2015). Is there a relationship between Parkinson's disease and Chlamydia pneumoniae?. Nigerian journal of clinical practice, 18(5), 612–615.en_US
dc.identifier.doi10.4103/1119-3077.154215
dc.identifier.endpage615en_US
dc.identifier.issn1119-3077
dc.identifier.issue5en_US
dc.identifier.pmid26096238
dc.identifier.scopus2-s2.0-84933519479
dc.identifier.scopusqualityQ2
dc.identifier.startpage612en_US
dc.identifier.urihttps://doi.org/10.4103/1119-3077.154215
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6103
dc.identifier.volume18en_US
dc.identifier.wosWOS:000356942700007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMedknow Publications & Media Pvt Ltden_US
dc.relation.ispartofNigerian Journal Of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChlamydia pneumoniaeen_US
dc.subjectetiologyen_US
dc.subjectParkinson's diseaseen_US
dc.titleIs there a relationship between Parkinsons disease and Chlamydia pneumoniaeen_US
dc.typeArticle

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